| ORIGINAL ARTICLE |
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| Year : 2005 | Volume
: 9
| Issue : 3 | Page : 133--136 |
Methylprednisolone as adjuvant in treatment of acute respiratory distress syndrome owing to leptospirosis-a pilot study
Abraham Ittyachen, VK Lakshmanakumar, CK Eapen, MR Joseph
Department of Medicine, India
Correspondence Address:
Abraham Ittyachen
Division of Critical Care & Emergency Services,M. O. S. C. Medical College, Kolenchery, Kerala State
India
  | 2 |
DOI: 10.4103/0972-5229.19677
Background: Acute respiratory distress syndrome (ARDS) owing to leptospirosis is associated with a high mortality. This is in spite of mechanical ventilation in a critical care setting. ARDS by its very nature, associated with economic constraints in our patients has made treating these patients a challenge. Objective: To study if combination of methylprednisolone and noninvasive ventilation is life-saving in ARDS owing to leptospirosis. Design: Interventional pilot study. Setting: Medical intensive care unit of a rural medical college hospital. Participants: Eight patients diagnosed to have ARDS owing to leptospirosis. Main outcome indicator: Survival. Results: Seven out of eight patients who were treated with methylprednisolone and noninvasive ventilation recovered fully to resume normal life. Conclusion: Methylprednisolone with noninvasive ventilation is life-saving in ARDS owing to leptospirosis.
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