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Year : 2005  |  Volume : 9  |  Issue : 3  |  Page : 133--136

Methylprednisolone as adjuvant in treatment of acute respiratory distress syndrome owing to leptospirosis-a pilot study

Department of Medicine, India

Correspondence Address:
Abraham Ittyachen
Division of Critical Care & Emergency Services,M. O. S. C. Medical College, Kolenchery, Kerala State
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0972-5229.19677

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Background: Acute respiratory distress syndrome (ARDS) owing to leptospirosis is associated with a high mortality. This is in spite of mechanical ventilation in a critical care setting. ARDS by its very nature, associated with economic constraints in our patients has made treating these patients a challenge. Objective: To study if combination of methylprednisolone and noninvasive ventilation is life-saving in ARDS owing to leptospirosis. Design: Interventional pilot study. Setting: Medical intensive care unit of a rural medical college hospital. Participants: Eight patients diagnosed to have ARDS owing to leptospirosis. Main outcome indicator: Survival. Results: Seven out of eight patients who were treated with methylprednisolone and noninvasive ventilation recovered fully to resume normal life. Conclusion: Methylprednisolone with noninvasive ventilation is life-saving in ARDS owing to leptospirosis.


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Online since 7th April '04
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