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Year : 2011  |  Volume : 15  |  Issue : 1  |  Page : 60

Novel H1N1 influenza infection in intensive care unit

Wiwanitkit House, Bangkhae, Bangkok, Thailand

Date of Web Publication22-Mar-2011

Correspondence Address:
Viroj Wiwanitkit
Wiwanitkit House, Bangkhae, Bangkok - 10160
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0972-5229.78232

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How to cite this article:
Wiwanitkit V. Novel H1N1 influenza infection in intensive care unit. Indian J Crit Care Med 2011;15:60

How to cite this URL:
Wiwanitkit V. Novel H1N1 influenza infection in intensive care unit. Indian J Crit Care Med [serial online] 2011 [cited 2018 May 23];15:60. Available from:

Dear Editor,

I read the recent report on novel H1N1 influenza infection by Chacko et al.,[1] with great interest. Chacko et al. concluded, "2009 H1N1 infection caused severe disease in relatively young patients without significant co-morbidities, characterized by severe hypoxemia and the requirement for prolonged mechanical ventilation" and "extra-pulmonary organ failure included circulatory and renal failure". [1] The data from this work are similar to a recent report from Spain. [2] I would like to add some discussions on this work. First, there is no doubt that the novel H1N1 influenza can cause severe disease in healthy subjects. However, based on this work, it might not be possible to note that all patients have no co-morbidities since there are no data on health status of all cases prior to the present illness. The cause of detected prolonged mechanical ventilation should be discussed. The presented data that the affected cases had to be on ventilator for a week or more is not different from the cases with classical H1N1 influenza virus infection. [3] This might be due to no significant difference in pathogenesis between classical and novel H1N1 influenza infections. Finally, the extrapulmonary organ failure is important. Although it is not common, it is detectable. [4] However, based on personal experience, it can be said that the heart failure is extremely rare. [5]

 » References Top

1.Chacko J, Gagan B, Ashok E, Radha M, Hemanth HV. Critically ill patients with 2009 H1N1 infection in an Indian ICU. Indian J Crit Care Med 2010;14:77-82.  Back to cited text no. 1
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2.Rello J, Rodríguez A, Ibañez P, Socias L, Cebrian J, Marques A, et al. H1N1 SEMICYUC Working Group. Intensive care adult patients with severe respiratory failure caused by Influenza A (H1N1)v in Spain. Crit Care Med 2009;13:148.  Back to cited text no. 2
3.Price DG, Symons JC. Influenza and respiratory failure. Br Med J 1970;1:233.   Back to cited text no. 3
4.Wiwanitkit V. Non respiratory manifestations of swine flu. Clin Ter 2009;160:499-501.  Back to cited text no. 4
5.Wiwanitkit V. Heart failure in swine flu: a note. J Card Fail 2009;15:812  Back to cited text no. 5

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Chacko, J., Gagan, B., Ashok, E., Radha, M., Hemanth, H.V.
Indian Journal of Critical Care Medicine. 2011; 15(1): 60-61


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