Indian Journal of Critical Care Medicine
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Year : 2011  |  Volume : 15  |  Issue : 2  |  Page : 71--77

Vasopressin: Its current role in anesthetic practice


1 Department of Anaesthesiology, College of Medicine and JNM Hospital, Kalyani, Nadia, India
2 Department of Gynaecology and Obstetrics, College of Medicine and JNM Hospital, Kalyani, Nadia, India
3 Department of Anesthesiology Perioperative Medicine and Pain, Apollo Gleneagles Hospitals, Kolkata, India

Correspondence Address:
Jayanta K Mitra
DL-31, Salt Lake, Sector II, Kolkata-700 091
India
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DOI: 10.4103/0972-5229.83006

PMID: 21814369

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Vasopressin or antidiuretic hormone is a potent endogenous hormone, which is responsible for regulating plasma osmolality and volume. In high concentrations, it also raises blood pressure by inducing moderate vasoconstriction. It acts as a neurotransmitter in the brain to control circadian rhythm, thermoregulation and adrenocorticotropic hormone release. The therapeutic use of vasopressin has become increasingly important in the critical care environment in the management of cranial diabetes insipidus, bleeding abnormalities, esophageal variceal hemorrhage, asystolic cardiac arrest and septic shock. After 10 years of ongoing research, vasopressin has grown to a potential component as a vasopressor agent of the anesthesiologist's armamentarium in the treatment of cardiac arrest and severe shock states.






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