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Indian Journal of Critical Care Medicine
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Year : 2012  |  Volume : 16  |  Issue : 1  |  Page : 55--57

Anaphylaxis to artesunate?

1 Department of Neuroanaesthesiology, All India Institute of Medical Sciences, New Delhi, India
2 Department of Microbiology, Pandit B.D. Sharma Post Graduate Institute of Medical Sciences, Rohtak, Haryana, India
3 Department of Anaesthesiology and Intensive Care, Institute of Medical Sciences, Banaras Hindu University,Varanasi, India

Correspondence Address:
G R Agrawal
Department of Anaesthesiology and Intensive Care, Institute of Medical Sciences, Banaras Hindu University, Varanasi 221005
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0972-5229.94440

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Artesunate, an artemissin derivative is a highly efficacious and relatively safe antimalarial agent. Common adverse reactions to artemissin derivatives are nausea, vomiting, anorexia and dizziness. More serious but less-frequent toxic effects of artesunate use are neutropenia, anemia, hemolysis, elevated liver enzymes and severe allergic reactions. However, anaphylactic reaction to artesunate is a rare entity. Here, we report a case of anaphylaxis to parenteral artesunate and its successful management in a female patient to whom intravenous artesunate was administered during surgery under general anesthesia.


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Online since 7th April '04
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