| CASE REPORT
|Year : 2012 | Volume
| Issue : 1 | Page : 55--57
Anaphylaxis to artesunate?
SK Dube1, PS Panda2, GR Agrawal3, DK Singh3
1 Department of Neuroanaesthesiology, All India Institute of Medical Sciences, New Delhi, India
2 Department of Microbiology, Pandit B.D. Sharma Post Graduate Institute of Medical Sciences, Rohtak, Haryana, India
3 Department of Anaesthesiology and Intensive Care, Institute of Medical Sciences, Banaras Hindu University,Varanasi, India
Artesunate, an artemissin derivative is a highly efficacious and relatively safe antimalarial agent. Common adverse reactions to artemissin derivatives are nausea, vomiting, anorexia and dizziness. More serious but less-frequent toxic effects of artesunate use are neutropenia, anemia, hemolysis, elevated liver enzymes and severe allergic reactions. However, anaphylactic reaction to artesunate is a rare entity. Here, we report a case of anaphylaxis to parenteral artesunate and its successful management in a female patient to whom intravenous artesunate was administered during surgery under general anesthesia.
G R Agrawal
Department of Anaesthesiology and Intensive Care, Institute of Medical Sciences, Banaras Hindu University, Varanasi 221005
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