LETTER TO THE EDITOR


https://doi.org/10.5005/jp-journals-10071-24503
Indian Journal of Critical Care Medicine
Volume 27 | Issue 8 | Year 2023

Comparison of Norepinephrine and Terlipressin vs Norepinephrine Alone for Management of Septic Shock: Few Concerns


Daisy Khera1https://orcid.org/0000-0002-2963-1370, Chethan Suresh2https://orcid.org/0000-0002-1270-2793

1,2Department of Pediatrics, All India Institute of Medical Sciences, Jodhpur, Rajasthan, India

Corresponding Author: Daisy Khera, Department of Pediatrics, All India Institute of Medical Sciences, Jodhpur, Rajasthan, India, Phone: 8003996913, e-mail: daisykhera78@gmail.com

How to cite this article: Khera D, Suresh C. Comparison of Norepinephrine and Terlipressin vs Norepinephrine Alone for Management of Septic Shock: Few Concerns. Indian J Crit Care Med 2023;27(8):605.

Source of support: Nil

Conflict of interest: None

Keywords: Intensive care unit, Norepinephrine, Sepsis, Shock, Terlipressin.

Dear Editor,

We read with interest the recently published research paper titled “Comparison of Norepinephrine and Terlipressin vs Norepinephrine Alone for Management of Septic Shock: A Randomized Control Study” by Sahoo P et al.1 It is a very well-done study and well-written as well. However, we have a few concerns which we have listed below:

ORCID

Daisy Khera https://orcid.org/0000-0002-2963-1370

Chethan Suresh https://orcid.org/0000-0002-1270-2793

REFERENCES

1. Sahoo P, Kothari N, Goyal S, Sharma A, Bhatia PK. Comparison of norepinephrine and terlipressin vs norepinephrine alone for management of septic shock: A randomized control study. Indian J Crit Care Med 2022;26(6):669–675. DOI: 10.5005/jp-journals-10071-24231.

2. Evans L, Rhodes A, Alhazzani W, Antonelli M, Coopersmith CM, French C, et al. Surviving sepsis campaign: International guidelines for management of sepsis and septic shock 2021. Intensive Care Med 2021;47(11):1181–1247. DOI: 10.1007/s00134-021-06506-y.

3. Guarracino F, Bertini P, Pinsky MR. Cardiovascular determinants of resuscitation from sepsis and septic shock. Crit Care 2019;23(1):118. DOI: 10.1186/s13054-019-2414-9.

4. Simpson SQ, Gaines M, Hussein Y, Badgett RG. Early goal-directed therapy for severe sepsis and septic shock: A living systematic review. J Crit Care 2016;36:43–48. DOI: 10.1016/j.jcrc.2016.06.017.

5. Balasubramanian H, Ananthan A, Rao S, Patole S. Odds ratio vs risk ratio in randomized controlled trials. Postgrad Med 2015;127(4):359–367. DOI: 10.1080/00325481.2015.1022494.

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