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VOLUME 10 , ISSUE 2 ( April, 2006 ) > List of Articles

CASE REPORT

Hemophagocytosis and miliary tuberculosis in a patient in the intensive care unit

F. Y. Khan, Zeinab Fawzy, Issar Siddiqui, Mohamed A. Yassin

Keywords : Hemophagocytosis, critically ill patient, miliary tuberculosis

Citation Information : Khan FY, Fawzy Z, Siddiqui I, Yassin MA. Hemophagocytosis and miliary tuberculosis in a patient in the intensive care unit. Indian J Crit Care Med 2006; 10 (2):112-114.

DOI: 10.4103/0972-5229.25924

License: CC BY-ND 3.0

Published Online: 01-04-2006

Copyright Statement:  Copyright © 2006; Jaypee Brothers Medical Publishers (P) Ltd.


Abstract

We report a 60-year-old woman who was admitted to our hospital with high-grade fever and dyspnea. Laboratory findings showed pancytopenia and examination of aspirated bone marrow showed mature histiocytes with marked hemophagocytosis. The patient′s condition continued to deteriorate despite adequate antibiotic coverage. Her respiratory condition worsened, so she was transferred to the ICU and ventilated. Transbroncheal biopsy was performed, which showed caseating granuloma suggesting pulmonary TB. Eight weeks later, bone marrow culture in Lowenstein media confirmed the presence of mycobacterium tuberculosis susceptible to INH, Rifampcine, pyrasinamide, ethambutol and streptomycin. Though anti-tuberculous therapy was started, she died after 28 days of hospitalization.


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