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VOLUME 13 , ISSUE 1 ( March, 2009 ) > List of Articles

RESEARCH ARTICLE

Aluminum phosphide poisoning: Effect of correction of severe metabolic acidosis on patient outcome

S. Jaiswal, R. K. Verma, N. Tewari

Keywords : Aluminum phosphide, arterial blood gases, poisoning, sodium bicarbonate

Citation Information : Jaiswal S, Verma RK, Tewari N. Aluminum phosphide poisoning: Effect of correction of severe metabolic acidosis on patient outcome. Indian J Crit Care Med 2009; 13 (1):21-24.

DOI: 10.4103/0972-5229.53111

License: CC BY-ND 3.0

Published Online: 01-03-2009

Copyright Statement:  Copyright © 2009; Jaypee Brothers Medical Publishers (P) Ltd.


Abstract

Forty patients of aluminum phosphide poisoning who were admitted to the ICU of Sir Sunder Lal Hospital, Banaras Hindu University, were studied. Restlessness, excessive thirst, shock, arrhythmias, tachypnoea, and severe metabolic acidosis were the common clinical findings. Only repeated and full correction with intravenous sodium bicarbonate was able to cope up with the severity and rapidity of acidosis. There was no significant change in blood pressure, pulse rate, and respiratory rate after full correction but gradually pulse and systolic blood pressure settled after ionotropic support in the survivors. There was significant improvement from 30.36% in the case when only half correction was done, as has been the common practice, to 57.5%, when full correction of metabolic acidosis was done.


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