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VOLUME 13 , ISSUE 1 ( March, 2009 ) > List of Articles


Severe myocardial depression in a patient with aluminium phosphide poisoning: A clinical, electrocardiographical and histopathological correlation

Viral Shah, Seema Baxi, Tanmay Vyas

Keywords : Aluminium phosphide, myocardial depression, myocyte vacuolation, myocytolysis, phosphide poisoning

Citation Information : Shah V, Baxi S, Vyas T. Severe myocardial depression in a patient with aluminium phosphide poisoning: A clinical, electrocardiographical and histopathological correlation. Indian J Crit Care Med 2009; 13 (1):41-43.

DOI: 10.4103/0972-5229.53117

License: CC BY-ND 3.0

Published Online: 01-04-2012

Copyright Statement:  Copyright © 2009; The Author(s).


Aluminium phosphide poisoning is very common in India. It is one of the most fatal poisons. The clinical spectrum of poisoning varies depending upon the dosage and duration of consumption. The main effect of the poison is due to the release of phosphine which inhibits cytochrome oxidase and thereby hampers cellular oxygen utilization. Almost any organ can be affected by aluminium phosphide poisoning. We report a case where the heart was the predominantly affected organ. We describe the clinical symptoms and signs and their correlation with electrocardiographic and histopathological examinations.

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