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VOLUME 15 , ISSUE 2 ( April, 2011 ) > List of Articles


Effectiveness of hemodialysis in a case of severe valproate overdose

Prashant Nasa, Deepak Sehrawat

Keywords : Anti-coma management, high-flux hemodialysis, hyperammonemia, valproate overdose

Citation Information : Nasa P, Sehrawat D. Effectiveness of hemodialysis in a case of severe valproate overdose. Indian J Crit Care Med 2011; 15 (2):120-122.

DOI: 10.4103/0972-5229.83020

License: CC BY-ND 3.0

Published Online: 01-08-2018

Copyright Statement:  Copyright © 2011; The Author(s).


A case of severe sodium valproate overdose is presented in which medicinal management failed to reverse coma of the patient. High-flux hemodialysis was then used to eliminate sodium valproate. This case demonstrated the effectiveness of hemodialysis in not only decreasing valproate levels very rapidly but also as an effective anti-coma management.

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