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VOLUME 16 , ISSUE 2 ( April, 2012 ) > List of Articles

CASE REPORT

A sound sleep

Alakendu Ghosh, Rudra Prosad Goswami, Swati Mondal, Subrata Basu, Partha Sarathi Karmakar

Keywords : Benzodiazepine, bilateral basal ganglia hyperintensity, India, MRI, poisoning

Citation Information : Ghosh A, Goswami RP, Mondal S, Basu S, Karmakar PS. A sound sleep. Indian J Crit Care Med 2012; 16 (2):106-108.

DOI: 10.4103/0972-5229.99128

License: CC BY-ND 3.0

Published Online: 01-04-2012

Copyright Statement:  Copyright © 2012; Jaypee Brothers Medical Publishers (P) Ltd.


Abstract

Benzodiazepine is a commonly encountered agent of poisoning, which is readily diagnosed by a pertinent history of drug ingestion and the clinical scenario. In the absence of a proper drug history, the diagnosis becomes challenging. Proper clinical assessment, urine assays and imaging play a very important role in reaching the diagnosis. We present a case of acute benzodiazepine poisoning without a history of drug intake. The key pointers toward diagnosis were an unarousable state with obstructive apnea. Magnetic resonance imaging (MRI) of the brain revealed peculiar symmetrical isolated globus pallidus T2 hyperintensity. We believe this to be the first report of isolated bilateral basal ganglia T2-weighted hyperintensity in MRI in the setting of acute benzodiazepine poisoning from India.


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