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VOLUME 16 , ISSUE 2 ( April, 2012 ) > List of Articles


Severe arrhythmia after lithium intoxication in a patient with bipolar disorder admitted to the intensive care unit

Mayra Gonçalves Menegueti, Anibal Basile-Filho, Olindo Assis Martins-Filho, Maria Auxiliadora-Martins

Keywords : Bipolar disorder, intensive care unit, life-threatening cardiac manifestations, lithium poisoning

Citation Information : Menegueti MG, Basile-Filho A, Martins-Filho OA, Auxiliadora-Martins M. Severe arrhythmia after lithium intoxication in a patient with bipolar disorder admitted to the intensive care unit. Indian J Crit Care Med 2012; 16 (2):109-111.

DOI: 10.4103/0972-5229.99134

License: CC BY-ND 3.0

Published Online: 01-12-2018

Copyright Statement:  Copyright © 2012; The Author(s).


Despite its narrow therapeutic index, lithium remains widely used as a mood stabilizer for the treatment of bipolar disease. The cardiac side-effects of lithium have been well documented, and may induce non-specific T-wave flattening, prolonged QT interval, sinus node dysfunction and also ventricular tachycardia and ventricular fibrillation. We report the case of a 61-year-old male patient diagnosed with bipolar disorder who developed life-threatening cardiac manifestations secondary to severe lithium poisoning. Although hemodialysis was performed and the arrhythmias were adequately treated, the patient died on the sixth day after hospital admission due hemorrhagic complications after tracheostomy.

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