Indian Journal of Critical Care Medicine

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VOLUME 17 , ISSUE 5 ( October, 2013 ) > List of Articles

CASE REPORT

Fatal overdose of iron tablets in adults

J. Jonathan Arul, Divya Bala

Keywords : Adults, fatal, iron tablets, overdose

Citation Information : Arul JJ, Bala D. Fatal overdose of iron tablets in adults. Indian J Crit Care Med 2013; 17 (5):311-313.

DOI: 10.4103/0972-5229.120326

License: CC BY-ND 3.0

Published Online: 00-10-2013

Copyright Statement:  Copyright © 2013; Jaypee Brothers Medical Publishers (P) Ltd.


Abstract

Acute iron toxicity is usually seen in children with accidental ingestion of iron-containing syrups. However, the literature on acute iron toxicity with suicidal intent in adults is scant. We report, the first instance of two adults with fatal ingestion of a single drug overdose with iron tablets from India. Two young adults developed severe gastro-intestinal bleeding and fulminant hepatic failure 48 h after deliberate consumption of large doses of iron tablets. Serum iron levels measured 36 h after ingestion were normal presumably due to the redistribution of iron to the intracellular compartment. Despite aggressive supportive management in medical intensive care unit of a tertiary care hospital, the patients succumbed to the toxic doses of iron.


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  1. Henretig FM, Temple AR. Acute iron poisoning in children. Emerg Med Clin North Am 1984;2:121-32.
  2. Baranwal AK, Singhi SC. Acute iron poisoning: Management guidelines. Indian Pediatr 2003;40:534-40.
  3. Robertson A, Tenenbein M. Hepatotoxicity in acute iron poisoning. Hum Exp Toxicol 2005;24:559-62.
  4. Kozaki K, Egawa H, Garcia-Kennedy R, Cox KL, Lindsay J, Esquivel CO. Hepatic failure due to massive iron ingestion successfully treated with liver transplantation. Clin Transplant 1995;9:85-7.
  5. Tenenbein M. Hepatotoxicity in acute iron poisoning. J Toxicol Clin Toxicol 2001;39:721-6.
  6. Olenmark M, Biber B, Dottori O, Rybo G. Fatal iron intoxication in late pregnancy. J Toxicol Clin Toxicol 1987;25:347-59.
  7. Schauben JL, Augenstein WL, Cox J, Sato R. Iron poisoning: Report of three cases and a review of therapeutic intervention. J Emerg Med 1990;8:309-19.
  8. Usama AM, Khaled IA, Mahmoud I. Determination of iron in blood serum by spectrophotometric and atomic absorption methods as a comparative study. Cukurova Med J 2013;38:358-64.
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