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VOLUME 17 , ISSUE 6 ( December, 2013 ) > List of Articles

CASE REPORT

Dramatic response to plasma exchange in systemic lupus erythematosus with acute complications: Report of two cases

Neelam Marwaha, Ratti Ram Sharma, Rekha Hans

Keywords : Diffuse alveolar hemorrhage, systemic lupus nephritis, therapeutic plasma exchange

Citation Information : Marwaha N, Sharma RR, Hans R. Dramatic response to plasma exchange in systemic lupus erythematosus with acute complications: Report of two cases. Indian J Crit Care Med 2013; 17 (6):385-387.

DOI: 10.4103/0972-5229.123462

License: CC BY-ND 3.0

Published Online: 00-12-2013

Copyright Statement:  Copyright © 2013; Jaypee Brothers Medical Publishers (P) Ltd.


Abstract

Acute exacerbations and complications are common in patients of systemic lupus erythematosus (SLE) despite of adequate long-term therapy with immunosuppressive drugs. So other options like therapeutic plasma exchange (TPE) can be considered as part of management. Here, we share our experience of two patients of SLE with acute complications who were successfully managed with TPE.


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  1. Szczepiorkowski ZM, Winters JL, Bandarenko N, Kim HC, Linenberger ML, Marques MB, et al. Guidelines on the use of therapeutic apheresis in clinical practice - Evidence-based approach from the Apheresis Applications Committee of the American Society for Apheresis. J Clin Apher 2010;25:83-177.
  2. Zamora MR, Warner ML, Tuder R, Schwarz MI. Diffuse alveolar hemorrhage and systemic lupus erythematosus. Clinical presentation, histology, survival, and outcome. Medicine (Baltimore) 1997;76:192-202.
  3. Hoshi K, Matsuda M, Ishikawa M, Mitsuhashi S, Gono T, Hashimoto T, et al. Successful treatment of fulminant pulmonary hemorrhage associated with systemic lupus erythematosus. Clin Rheumatol 2004;23:252-5.
  4. Huang DF, Tsai ST, Wang SR. Recovery of both acute massive pulmonary hemorrhage and acute renal failure in a systemic lupus erythematosus patient with lupus anticoagulant by the combined therapy of plasmapheresis plus cyclophosphamide. Transfus Sci 1994;15:283-8.
  5. Frank MM, Hamburger MI, Lawley TJ, Kimberly RP, Plotz PH. Defective reticuloendothelial system Fc-receptor function in systemic lupus erythematosus. N Engl J Med 1979;300:518-23.
  6. Lockwood CM, Worlledge S, Nicholas A, Cotton C, Peters DK. Reversal of impaired splenic function in patients with nephritis or vasculitis (or both) by plasma exchange. N Engl J Med 1979;300:524-30.
  7. Santos-Ocampo AS, Mandell BF, Fessler BJ. Alveolar hemorrhage in systemic lupus erythematosus: Presentation and management. Chest 2000;118:1083-90.
  8. Hussein M, Mooij J, Roujouleh H, El Sayed H. The role of plasmapheresis in the treatment of severe lupus nephritis: A case report. Saudi J Kidney Dis Transpl 1995;6:412-6.
  9. Lewis EJ, Hunsicker LG, Lan SP, Rohde RD, Lachin JM. A controlled trial of plasmapheresis therapy in severe lupus nephritis. The Lupus Nephritis Collaborative Study Group. N Engl J Med 1992;326:1373-9.
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