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VOLUME 18 , ISSUE 4 ( April, 2014 ) > List of Articles


Methylene blue unresponsive methemoglobinemia

Manivachagan Natarajan, Ebor James, Kala Ebenezer

Keywords : Co-oximetry, exchange transfusion, methemoglobinemia, methylene blue

Citation Information : Natarajan M, James E, Ebenezer K. Methylene blue unresponsive methemoglobinemia. Indian J Crit Care Med 2014; 18 (4):253-255.

DOI: 10.4103/0972-5229.130582

License: CC BY-ND 3.0

Published Online: 01-04-2005

Copyright Statement:  Copyright © 2014; The Author(s).


Acquired methemoglobinemia is an uncommon blood disorder induced by exposure to certain oxidizing agents and drugs. Although parents may not give any history of toxin ingestion; with the aid of pulse-oximetry and blood gas analysis, we can diagnose methemoglobinemia. Prompt recognition of this condition is required in emergency situations to institute early methylene blue therapy. We report an unusual case of severe toxic methemoglobinemia, which did not respond to methylene blue, but was successfully managed with exchange transfusion.

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