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VOLUME 18 , ISSUE 6 ( June, 2014 ) > List of Articles


Heparin thromboprophylaxis in critically ill patients: Is it really changing outcome?

Mohan Gurjar

Citation Information : Gurjar M. Heparin thromboprophylaxis in critically ill patients: Is it really changing outcome?. Indian J Crit Care Med 2014; 18 (6):345-347.

DOI: 10.4103/0972-5229.133867

License: CC BY-ND 3.0

Published Online: 01-06-2014

Copyright Statement:  Copyright © 2014; The Author(s).


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  1. Chan CM, Shorr AF. Venous thromboembolic disease in the intensive care unit. Semin Respir Crit Care Med 2010;31:39-46.
  2. Crowther MA, Cook DJ, Griffith LE, Devereaux PJ, Rabbat CC, Clarke FJ, et al. Deep venous thrombosis: Clinically silent in the intensive care unit. J Crit Care 2005;20:334-40.
  3. Saigal S, Sharma JP, Joshi R, Singh DK. Thromboprophylaxis in acutely ill medical and critically ill patients. Indian J Crit Care Med 2014;382-91.
  4. Cade JF. High risk of the critically ill for venous thromboembolism. Crit Care Med 1982;10:448-50.
  5. Alhazzani W, Lim W, Jaeschke RZ, Murad MH, Cade J, Cook DJ. Heparin thromboprophylaxis in medical-surgical critically ill patients: A systematic review and meta-analysis of randomized trials. Crit Care Med 2013;41:2088-98.
  6. Ribic C, Lim W, Cook D, Crowther M. Low-molecular-weight heparin thromboprophylaxis in medical-surgical critically ill patients: A systematic review. J Crit Care 2009;24:197-205.
  7. Robinson S, Zincuk A, Larsen UL, Ekstrüm C, Nybo M, Rasmussen B, et al. A comparative study of varying doses of enoxaparin for thromboprophylaxis in critically ill patients: A double-blinded, randomised controlled trial. Crit Care. 2013;17 (2):R75. [Epub ahead of print].
  8. Douketis J, Cook D, Meade M, Guyatt G, Geerts W, Skrobik Y, et al. Canadian Critical Care Trials Group. Prophylaxis against deep vein thrombosis in critically ill patients with severe renal insufficiency with the low-molecular-weight heparin dalteparin: An assessment of safety and pharmacodynamics: The DIRECT study. Arch Intern Med. 2008;168:1805-12.
  9. Lamontagne F, McIntyre L, Dodek P, Heels-Ansdell D, Meade M, Pemberton J, et al. PROTECT (Prophylaxis for Thromboembolism in Critical Care Trial) Investigators. Nonleg venous thrombosis in critically ill adults: A nested prospective cohort study. JAMA Intern Med 2014;174:689-96.
  10. Kakkos SK, Caprini JA, Geroulakos G, Nicolaides AN, Stansby GP, Reddy DJ. Combined intermittent pneumatic leg compression and pharmacological prophylaxis for prevention of venous thromboembolism in high-risk patients. Cochrane Database Syst Rev 2008 8;(4):CD005258.
  11. Kahn SR, Lim W, Dunn AS, Cushman M, Dentali F, Akl EA, et al. American College of Chest Physicians. Prevention of VTE in nonsurgical patients: Antithrombotic Therapy and Prevention of Thrombosis, 9 th ed.: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines. Chest 2012;141 (2 Suppl):e195S-226S.
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