Indian Journal of Critical Care Medicine

Register      Login

SEARCH WITHIN CONTENT

FIND ARTICLE

Volume / Issue

Online First

Archive
Related articles

VOLUME 18 , ISSUE 6 ( June, 2014 ) > List of Articles

CASE REPORT

Transfusion associated circulatory overload

Naveen Agnihotri, Ajju Agnihotri

Keywords : Blood transfusion, blood transfusion reaction, risk factors, transfusion associated circulatory overload

Citation Information : Agnihotri N, Agnihotri A. Transfusion associated circulatory overload. Indian J Crit Care Med 2014; 18 (6):396-398.

DOI: 10.4103/0972-5229.133938

License: CC BY-ND 3.0

Published Online: 01-06-2014

Copyright Statement:  Copyright © 2014; Jaypee Brothers Medical Publishers (P) Ltd.


Abstract

Transfusion associated circulatory overload (TACO) is an established, but grossly under diagnosed and underreported complication of blood transfusion. We present the case of a 46-year-old diabetic and hypertensive patient admitted to our hospital for recurrent episodes of urinary retention. Over initial 3 days of the admission, the patient received multiple units of packed red blood cells (RBC) and fresh frozen plasma, uneventfully. However, the patient developed signs and symptoms suggestive of TACO with only small amount of the 4 th unit of RBC. The patient had to be shifted to the Intensive Care Unit for further management of this complication. Etiology of TACO is more complex than a mere circulatory overload and is still not completely understood. TACO leads to a prolonged hospital stay and morbidity in the patients developing this complication. TACO thus needs to be suspected in patients at risk for this complication.


PDF Share
  1. Pandey S, Vyas GN. Adverse effects of plasma transfusion. Transfusion 2012;52 Suppl 1:65S-79.
  2. Narick C, Triulzi DJ, Yazer MH. Transfusion-associated circulatory overload after plasma transfusion. Transfusion 2012;52:160-5.
  3. Blumberg N, Heal JM, Gettings KF, Phipps RP, Masel D, Refaai MA, et al. An association between decreased cardiopulmonary complications transfusion-related acute lung injury and transfusion-associated circulatory overload and implementation of universal leukoreduction of blood transfusions. Transfusion 2010;50:2738-44.
  4. Li G, Kojicic M, Reriani MK, Fernández Pérez ER, Thakur L, Kashyap R, et al. Long-term survival and quality of life after transfusion-associated pulmonary edema in critically ill medical patients. Chest 2010;137:783-9.
  5. Bux J, Sachs UJ. Pulmonary transfusion reactions. Transfus Med Hemother 2008;35:337-45.
  6. Bolton-Maggs PH, Cohen H On Behalf of the Serious Hazards of Transfusion (SHOT) Steering Group. The 2011 Annual SHOT Report, 2012. Available from: http://www.shotuk.org/wp-content/uploads/2012/07/shot-annual-report_FinalWebVersionBookmarked_2012_06_22.pdf. [Last accessed on 2013 May 01]
  7. Alam A, Lin Y, Lima A, Hansen M, Callum JL. The prevention of transfusion-associated circulatory overload. Transfus Med Rev 2013;27:105-12.
  8. Popovsky MA, Robillard P, Schipperus M, Stainsby D, Tissot JD, Wiersum J. ISBT Working Party on Hemovigilance. Proposed standard definitions for surveillance of noninfectious adverse transfusion reactions, 2006. Available from: http://www.ihn-org.com/wp-content/uploads/2011/06/ISBT-definitions-for-non-infectious-transfusion-reactions.pdf. [Last accessed on 2013 May 01].
PDF Share
PDF Share

© Jaypee Brothers Medical Publishers (P) LTD.