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VOLUME 18 , ISSUE 6 ( June, 2014 ) > List of Articles


Management of life-threatening calcium channel blocker overdose with continuous veno-venous hemodiafiltration with charcoal hemoperfusion

Suneel K. Garg, Pankaj K. Goyal, Alka Bhasin

Keywords : Amlodipine overdose, calcium channel blocker overdose, charcoal hemoperfusion, continuous veno-venous hemodiafiltration

Citation Information : Garg SK, Goyal PK, Bhasin A. Management of life-threatening calcium channel blocker overdose with continuous veno-venous hemodiafiltration with charcoal hemoperfusion. Indian J Crit Care Med 2014; 18 (6):399-401.

DOI: 10.4103/0972-5229.133939

License: CC BY-ND 3.0

Published Online: 01-04-2006

Copyright Statement:  Copyright © 2014; The Author(s).


Cases of calcium channel blocker overdose reported from India are few, and although rare, they are associated with high mortality. Management includes fluids, vasopressors, calcium gluconate or chloride, glucagon infusion, and hyperinsulinemia-euglycemia therapy along with some rescue therapies tried in anecdotal reports. We report here a case of life-threatening overdose of amlodipine with shock, refractory to conventional therapies. Salvage therapy with continuous veno-venous hemodiafiltration using charcoal hemoperfusion with prior infusion of intravenous lipid emulsion resulted in a successful outcome.

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