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VOLUME 18 , ISSUE 8 ( August, 2014 ) > List of Articles


Spontaneous cryptococcal peritonitis with fungemia in patients with decompensated cirrhosis: Report of two cases

Vikram Bhatia, Deepak Saini, Vikas Khillan, Neha Rathor, Chinmaya Kumar Bal, Ripu Daman, Shiv Kumar Sarin

Keywords : Cirrhosis, Cryptococcus neoformans, India ink staining, spontaneous bacterial peritonitis, spontaneous cryptococcal peritonitis

Citation Information : Bhatia V, Saini D, Khillan V, Rathor N, Bal CK, Daman R, Sarin SK. Spontaneous cryptococcal peritonitis with fungemia in patients with decompensated cirrhosis: Report of two cases. Indian J Crit Care Med 2014; 18 (8):536-539.

DOI: 10.4103/0972-5229.138161

License: CC BY-ND 3.0

Published Online: 01-07-2007

Copyright Statement:  Copyright © 2014; The Author(s).


Cryptococcus neoformans is encapsulated yeast that predominately infects immunocompromised individuals. Liver disease is an under-recognized predisposition for cryptococcal disease. We report two nonalcoholic, nondiabetic, and human immunodeficiency virus - negative cirrhotic patients, with spontaneous cryptococcal peritonitis. Cryptococcus infection was diagnosed by culture of ascitic fluid and peripheral blood in both. We treated the first patient with amphotericin-B, but he expired. The second patient with earlier diagnosis, survived to discharge with fluconazole treatment. We suggest a high clinical suspicion for Cryptococcus as a possible etiology of spontaneous peritonitis in cirrhotic patients.

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