Phenol burns can result in multiple organ failure. This is a case report of acute severe phenol dermal burn after accidental splash of 94% phenol on 35-year-old patient′s body who was brought to hospital after 90 min of exposure. Decontamination was done with high-density water and glycerol. Early complications in form of metabolic acidosis and acute renal failure required hemodialysis. Extensive protein denaturation was managed with IV albumin and high protein diet. Patient also developed pleural effusion and acute respiratory distress syndrome, but these were successfully managed by intercostal drain tube insertion and noninvasive ventilation. The patient survived after multiple organ failures and widespread burns despite the fact that it has been observed that outcome of phenol burns with >60 2 inches of skin affected or two or more organs failure involving renal system is nearly fatal.
Lin TM, Lee SS, Lai CS. Phenol Burn. Burns 2005;32 :517-21. Available from: http://www.researchgate.net/publication/7159558_Phenol_burn. http://dx.doi.org/10.1016/j.burns.2005.12.016. [Last ccess on 2015 Apr 18]
Bruce RM, Santodonato J, Neal MW. Summary review of the health effects associated with phenol. Toxicol Ind Health 1987;3:535-68.
Lin CH, Yang JY. Chemical burn with cresol intoxication and multiple organ failure. Burns 1992;18:162-6.
Agency for Toxic Substances and Disease Registry. Medical Management Guidelines for Phenol. 2014. Available from: http://www.atsdr.cdc.gov/mmg/mmg.asp?id=144&tid=27. [Last access on 2015 Apr 18].
Pardoe R, Minami RT, Sato RM, Schlesinger SL. Phenol burns. Burns 1976;3:29-41.
Sugden P, Levy M, Rao GS. Onychocryptosis-phenol burn fiasco. Burns: Journal of the International Society for Burn Injuries 2001;27:289.
University Hospital Consortium. (2010). GUIDELINES FOR USE OF ALBUMIN. Archives of Internal Medicine. 2010. Available from: https://www.universityhealthsystem.com/files/frontEnd/pharmacy/Albumin_Guidelines_UHS_April_2010.pdf. [Last access on 2015 Apr 18]
Lewington A, Kanagasundaram S. Renal Association Clinical Practice Guidelines on acute kidney injury. Nephron Clin Pract 2011;118 Suppl 1:c349-90.
Ferrer M, Esquinas A, Leon M, Gonzalez G, Alarcon A, Torres A. Noninvasive ventilation in severe hypoxemic respiratory failure: A randomized clinical trial. Am J Respir Crit Care Med 2003;168:1438-44.
