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VOLUME 20 , ISSUE 1 ( 2016 ) > List of Articles

CASE REPORT

Stuck with pancytopenia in dengue fever: Evoke for hemophagocytic syndrome

Manoj Lakhotia, Hans Raj Pahadiya, Ronak Gandhi, Gopal Raj Prajapati, Akanksha Choudhary

Keywords : hemophagocytic lymphohistiocytosis, pancytopenia,Dengue fever

Citation Information : Lakhotia M, Pahadiya HR, Gandhi R, Prajapati GR, Choudhary A. Stuck with pancytopenia in dengue fever: Evoke for hemophagocytic syndrome. Indian J Crit Care Med 2016; 20 (1):55-56.

DOI: 10.4103/0972-5229.173695

License: CC BY-ND 3.0

Published Online: 00-01-2016

Copyright Statement:  Copyright © 2016; Jaypee Brothers Medical Publishers (P) Ltd.


Abstract

The hemophagocytic syndrome is an atypical and rare manifestation of dengue fever (DF). We describe a 15-year-old girl developing DF associated hemophagocytic syndrome who responded with supportive treatment.


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  1. Rajagopala S, Singh N, Agarwal R, Gupta D, Das R. Severe hemophagocytic lymphohistiocytosis in adults-experience from an intensive care unit from North India. Indian J Crit Care Med 2012;16:198-203.
  2. Henter JI, Horne A, Aricó M, Egeler RM, Filipovich AH, Imashuku S, et al. HLH-2004: Diagnostic and therapeutic guidelines for hemophagocytic lymphohistiocytosis. Pediatr Blood Cancer 2007;48:124-31.
  3. Janka G, zur Stadt U. Familial and acquired hemophagocytic lymphohistiocytosis. Hematology Am Soc Hematol Educ Program 2005;1:82-8.
  4. Fisman DN. Hemophagocytic syndromes and infection. Emerg Infect Dis 2000;6:601-8.
  5. Ramachandran B, Balasubramanian S, Abhishek N, Ravikumar KG, Ramanan AV. Profile of hemophagocytic lymphohistiocytosis in children in a tertiary care hospital in India. Indian Pediatr 2011;48:31-5.
  6. Tan LH, Lum LC, Omar SF, Kan FK. Hemophagocytosis in dengue: Comprehensive report of six cases. J Clin Virol 2012;55:79-82.
  7. Fink J, Gu F, Vasudevan SG. Role of T cells, cytokines and antibody in dengue fever and dengue haemorrhagic fever. Rev Med Virol 2006;16:263-75.
  8. Martina BE, Koraka P, Osterhaus AD. Dengue virus pathogenesis: An integrated view. Clin Microbiol Rev 2009;22:564-81.
  9. Ohga S, Matsuzaki A, Nishizaki M, Nagashima T, Kai T, Suda M, et al. Inflammatory cytokines in virus-associated hemophagocytic syndrome. Interferon-gamma as a sensitive indicator of disease activity. Am J Pediatr Hematol Oncol 1993;15:291-8.
  10. Jordan MB, Allen CE, Weitzman S, Filipovich AH, McClain KL. How I treat hemophagocytic lymphohistiocytosis. Blood 2011;118:4041-52.
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