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VOLUME 20 , ISSUE 10 ( 2016 ) > List of Articles


An encounter with enalapril-induced resistant, life-threatening angioedema at rural health center in Botswana

Nikhil Anish, Abiy Gabremedhin

Keywords : Angioedema, angiotensin-converting enzyme inhibitor, difficult airway, enalapril, fresh-frozen plasma

Citation Information : Anish N, Gabremedhin A. An encounter with enalapril-induced resistant, life-threatening angioedema at rural health center in Botswana. Indian J Crit Care Med 2016; 20 (10):613-616.

DOI: 10.4103/0972-5229.192060

License: CC BY-ND 3.0

Published Online: 01-09-2017

Copyright Statement:  Copyright © 2016; The Author(s).


Angioedema, a rare, potentially fatal and usually self-limiting adverse effect of therapy with enalapril, is always a challenging encounter for an intensive care specialist in a rural setup. Here, we present a 74-year-old female, who presented to the Emergency Department of Sekgoma Memorial Hospital, Serowe village, Botswana, with progressive swelling of her face, tongue and breathing difficulty just 2 days after starting tablet enalapril. She failed to respond to usual treatment with adrenaline, steroids, and H1-antihistaminic agent, but she responded well with intravenous fresh-frozen plasma infusion. This helped us manage a difficult airway situation in a less equipped rural health center.

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