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VOLUME 20 , ISSUE 6 ( 2016 ) > List of Articles


Successful management of zinc phosphide poisoning

Sayed Marashi, Vahid Shakoori, Mahsa Agahi, Maryam Vasheghani-Farahani

Keywords : Management, poisoning, zinc phosphide

Citation Information : Marashi S, Shakoori V, Agahi M, Vasheghani-Farahani M. Successful management of zinc phosphide poisoning. Indian J Crit Care Med 2016; 20 (6):368-370.

DOI: 10.4103/0972-5229.183907

License: CC BY-ND 3.0

Published Online: 01-01-2014

Copyright Statement:  Copyright © 2016; The Author(s).


Zinc phosphide (Zn2P3) rodenticide, is generally misused intentionally for suicidal purpose in Iran. For many years, scientists believe that liberation of phosphine (PH3) on contact with acidic content of the stomach is responsible for clinical presentations. However, relatively long time interval between ingestion of Zn2P3and presentation of its systemic toxicity, and progression of acute liver failure could not be explained by the current opinion. Hence, an innovative theory intended that phosphonium, as an intermediate product will create and pass through the stomach, which then will reduce to produce PH3in the luminal tract. Here, we present a case of massive Zn2P3poisoning. In our case, we used repeated doses of castor oil to induce bowel movement with an aim of removing unabsorbed toxin, which was proved by radiography. Interestingly, the patient presents only mild symptoms of toxicity such as transient metabolic acidosis and hepatic dysfunction.

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