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VOLUME 20 , ISSUE 6 ( 2016 ) > List of Articles

CASE REPORT

Thrombotic microangiopathy as an initial manifestation in HIV patients

Thanigachalam Dineshkumar, Jeyachandran Dhanapriya, Palanivel Jaganathan, Ramanathan Sakthirajan, Natarajan Gopalakrishnan, T Balasubramaniyan

Keywords : HIV, renal failure, thrombotic microangiopathy,Antiretroviral therapy

Citation Information : Dineshkumar T, Dhanapriya J, Jaganathan P, Sakthirajan R, Gopalakrishnan N, Balasubramaniyan T. Thrombotic microangiopathy as an initial manifestation in HIV patients. Indian J Crit Care Med 2016; 20 (6):374-376.

DOI: 10.4103/0972-5229.183903

License: CC BY-ND 3.0

Published Online: 00-06-2016

Copyright Statement:  Copyright © 2016; Jaypee Brothers Medical Publishers (P) Ltd.


Abstract

Thrombotic microangiopathy (TMA) is characterized by microangiopathic hemolytic anemia, thrombocytopenia, microvascular thrombosis, and various organ dysfunctions. TMA usually occurs in a more advanced stage of HIV disease. TMA as an initial presenting feature is rare. We here report a male patient who presented with oliguric renal failure. Investigations revealed anemia, thrombocytopenia, schistocytes in peripheral smear, and HIV-positive. Renal biopsy revealed TMA. He was treated with hemodialysis and started on highly active antiretroviral therapy.


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