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VOLUME 21 , ISSUE 4 ( 2017 ) > List of Articles

CASE REPORT

Not all febrile critical illness with rash is infective: Drug reaction may be a mimic

Ashok K Pannu, M. B. Adarsh

Keywords : Drug rash with eosinophilia and systemic symptoms, LEMDS, multi-organ dysfunction, tropical fever

Citation Information : Pannu AK, Adarsh MB. Not all febrile critical illness with rash is infective: Drug reaction may be a mimic. Indian J Crit Care Med 2017; 21 (4):229-231.

DOI: 10.4103/ijccm.IJCCM_397_16

License: CC BY-ND 3.0

Published Online: 01-05-2018

Copyright Statement:  Copyright © 2017; The Author(s).


Abstract

We report a case of ciprofloxacin-related drug rash with eosinophilia and systemic symptoms (DRESS) which was initially diagnosed and managed on the line of tropical fever. Later, a diagnosis of definite case of DRESS was made according to the RegiSCAR scoring system and the patient was managed with the removal of ciprofloxacin along with steroids. DRESS is a great masquerader. The diagnosis should be highly suspected in the presence of fever, skin rash, liver involvement, and hypereosinophilia.


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  1. Singhi S, Chaudhary D, Varghese GM, Bhalla A, Karthi N, Kalantri S, et al. Tropical fevers: Management guidelines. Indian J Crit Care Med 2014;18:62-9.
  2. Gentile I, Talamo M, Borgia G. Is the drug-induced hypersensitivity syndrome (DIHS) due to human herpesvirus 6 infection or to allergy-mediated viral reactivation? Report of a case and literature review. BMC Infect Dis 2010;10:49.
  3. Bocquet H, Bagot M, Roujeau JC. Drug-induced pseudolymphoma and drug hypersensitivity syndrome (drug rash with eosinophilia and systemic symptoms: DRESS). Semin Cutan Med Surg 1996;15:250-7.
  4. Kano Y, Ishida T, Hirahara K, Shiohara T. Visceral involvements and long-term sequelae in drug-induced hypersensitivity syndrome. Med Clin North Am 2010;94:743-59, xi.
  5. Kardaun SH, Sidoroff A, Valeyrie-Allanore L, Halevy S, Davidovici BB, Mockenhaupt M, et al. Variability in the clinical pattern of cutaneous side-effects of drugs with systemic symptoms: Does a DRESS syndrome really exist? Br J Dermatol 2007;156:609-11.
  6. Ben m'rad M, Leclerc-Mercier S, Blanche P, Franck N, Rozenberg F, Fulla Y, et al. Drug-induced hypersensitivity syndrome: Clinical and biologic disease patterns in 24 patients. Medicine (Baltimore) 2009;88:131-40.
  7. Tas S, Simonart T. Management of drug rash with eosinophilia and systemic symptoms (DRESS syndrome): An update. Dermatology 2003;206:353-6.
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