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VOLUME 21 , ISSUE 7 ( 2017 ) > List of Articles


A Rare Case of Strongyloides Hyperinfection from Hypogammaglobulinemia

Sujith M. Thomas, A Rajalakshmi

Keywords : Agammaglobulinemia, autoinfection, cell-mediated immunity, humoral immunity, parasites, Strongyloides

Citation Information : Thomas SM, Rajalakshmi A. A Rare Case of Strongyloides Hyperinfection from Hypogammaglobulinemia. Indian J Crit Care Med 2017; 21 (7):466-468.

DOI: 10.4103/ijccm.IJCCM_139_17

License: CC BY-ND 3.0

Published Online: 01-07-2018

Copyright Statement:  Copyright © 2017; The Author(s).


Strongyloides infection can range from asymptomatic eosinophilia to disseminated disease. Common in tropical and subtropical nations, it can lead to hyperinfection, an autoinfection increasing parasitic burden in immunocompromised. Cell-mediated immunity is important in combating parasite infection. We present a case of Strongyloides hyperinfection in hypogammaglobulinemia which was refractory to conventional treatment but responded to immunoglobulin administration with complete resolution indicating role of humoral immunity also.

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