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VOLUME 22 , ISSUE 10 ( 2018 ) > List of Articles


“BROAD effect: Bradycardia in obstructive airway disease”An unusual phenomenon: A case report

Sandeep Chopra, Vikas Sikri

Keywords : Bradycardia, noninvasive ventilation, recurrent

Citation Information : Chopra S, Sikri V. “BROAD effect: Bradycardia in obstructive airway disease”An unusual phenomenon: A case report. Indian J Crit Care Med 2018; 22 (10):757-759.

DOI: 10.4103/ijccm.IJCCM_285_18

License: CC BY-ND 3.0

Published Online: 01-12-2017

Copyright Statement:  Copyright © 2018; The Author(s).


Non Invasive Ventilation (NIV) is frequently used in Obstructive Airway Disease (OAD) especially COPD (Chronic Obstructive Pulmonary Disease). Patients often get hypoxic or retain carbon dioxide during attempts to feed the patient orally or trial of intermittent support. However, patient developing sudden bradycardia by mere taking off the mask and reverting to sinus rhythm as soon as mask is put back is extremely rare. We present one such case that was also a treatment challenge for us. Recurrent bradycardia in COPD, with repeatability on discontinuation of Non Invasive Ventilation (NIV) is an extremely rare condition with not much reports/studies in the medical literature. The mechanisms leading to such an event are poorly understood. To the best of our knowledge, it's the first case to be reported from India.

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  1. Echevarria C, Bourke SC, Gibson GJ. Profound bradycardia associated with NIV removal. Respir Med Case Rep 2012;5:73-5.
  2. Robert R, Malin F, Bauwens M, Amiel A, Patte D. Severe non-hypoxic bradycardia during disconnection from the ventilator during the recovery phase of ARDS. Intensive Care Med 1991;17:494-6.
  3. Sukegawa M, Noda A, Sugiura T, Nakata S, Yoshizaki S, Soga T. Assessment of continuous positive airway pressure treatment in obstructive sleep apnea syndrome using 24-hour urinary catecholamines. Clin Cardiol 2005;28:519-22.
  4. Minemura H, Akashiba T, Yamamoto H, Akahoshi T, Kosaka N, Horie T, et al. Acute effects of nasal continuous positive airway pressure on 24-hour blood pressure and catecholamines in patients with obstructive sleep apnea. Intern Med 1998;37:1009-13.
  5. Marrone O, Riccobono L, Salvaggio A, Mirabella A, Bonanno A, Bonsignore MR, et al. Catecholamines and blood pressure in obstructive sleep apnea syndrome. Chest 1993;103:722-7.
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