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VOLUME 22 , ISSUE 2 ( 2018 ) > List of Articles
Keywords : Fondaparinux, heparin-induced thrombocytopenia, thromboprophylaxis treatment
Citation Information : Peshattiwar V. The Fondaparinux Paradox: Fondaparinux-Related Heparin-Induced Thrombocytopenia. Indian J Crit Care Med 2018; 22 (2):116-118.
License: CC BY-ND 3.0
Published Online: 01-02-2018
Copyright Statement: Copyright © 2018; Jaypee Brothers Medical Publishers (P) Ltd.
Fondaparinux, a pentasaccharide administered for heparin-induced thrombocytopenia (HIT), can lead to the occurrence of thrombocytopenia. This patient underwent aortic stent graft placement for Salmonella paratyphi A-infected abdominal aortic aneurysm. Fondaparinux was administered for anticoagulation that led to a dramatic decline in his platelet counts. Investigations revealed HIT profile, PF4/heparin by particle gel immunoassay to be positive. Fondaparinux, a prescribed anticoagulant for HIT can paradoxically predispose to thrombocytopenia.
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