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VOLUME 22 , ISSUE 5 ( 2018 ) > List of Articles

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Clinicoetiological pattern and outcome of neonates requiring mechanical ventilation: Study in a tertiary care centre

Mohini Yadav, Gauri Chauhan, A. Bhardwaj, P. Sharma

Keywords : hyaline membrane disease, mechanical ventilation, meconium aspiration syndrome, sepsis,APGAR

Citation Information : Yadav M, Chauhan G, Bhardwaj A, Sharma P. Clinicoetiological pattern and outcome of neonates requiring mechanical ventilation: Study in a tertiary care centre. Indian J Crit Care Med 2018; 22 (5):361-363.

DOI: 10.4103/ijccm.IJCCM_452_17

License: CC BY-ND 3.0

Published Online: 00-05-2018

Copyright Statement:  Copyright © 2018; Jaypee Brothers Medical Publishers (P) Ltd.


Abstract

The clinical and etiological pattern of ventilated newborns, their outcome in relation to morbidity and mortality was studied with 50 ventilated newborns, including outborns. M:f ratio was 2.1:1. The most common gestational age 28–36 weeks (60%) and mostly were appropriate for gestational age (66%). Survival rate 40% (20/50) being directly proportional to the gestational age and intrauterine growth pattern (P < 0.01). Babies by LSCS Lower Segment Cessarian Section survived more than born by normal vaginal delivery (46.7% vs. 37.1%). More outborn survival could be related to their advanced gestational age on presentation. The initial assessment of APGAR score of >7 had a better outcome (56.3%; P < 0.03). The most common indication of ventilation was hyaline membrane disease (19/50) but the survival rate best in babies with meconium aspiration syndrome (54.5%). The most prevalent complication was sepsis (survival rate 60%) while conditions such as shock, intraventricular hemorrhage, disseminated intravascular coagulation, air leak syndrome, and pulmonary hemorrhage had 100% mortality. Thus, the outcome as survival is constrained by many factors; newborn\'s profile, conditions at birth, and postnatal resuscitation.


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