Indian Journal of Critical Care Medicine

Register      Login



Volume / Issue

Online First

Related articles

VOLUME 22 , ISSUE 7 ( 2018 ) > List of Articles


Chondrodysplasia punctata with severe airway stenosis

Viswas Chhapola, Bobbity Deepthi, Sandeep Kanwal, Ankita Sharma

Keywords : Airway stenosis, chondrodysplasia punctata, Conradi disease, tracheal calcifications

Citation Information : Chhapola V, Deepthi B, Kanwal S, Sharma A. Chondrodysplasia punctata with severe airway stenosis. Indian J Crit Care Med 2018; 22 (7):552-554.

DOI: 10.4103/ijccm.IJCCM_105_18

License: CC BY-ND 3.0

Published Online: 01-04-2015

Copyright Statement:  Copyright © 2018; The Author(s).


Chondrodysplasia punctata (CDP) is a group of skeletal dysplasias characterized primarily by punctate calcifications in cartilage. It is a rare disease with an incidence of 1:100,000 live births. Extensive airway involvement with calcification of tracheal, bronchial, and thyroid cartilage in CDP is an infrequent finding. We aim to report a case of CDP with characteristic radiological features and severe airway involvement.

PDF Share
  1. Irving MD, Chitty LS, Mansour S, Hall CM. Chondrodysplasia punctata: A clinical diagnostic and radiological review. Clin Dysmorphol 2008;17:229-41.
  2. Jurkiewicz E, Marcinska B, Bothur-Nowacka J, Dobrzanska A. Clinical and radiological pictures of two newborn babies with manifestations of chondrodysplasia punctata and review of available literature. Pol J Radiol 2013;78:57-64.
  3. Goussard P, Andronikou S, Semakula-Katende NS, Gie R. Calcification and airway stenosis in a child with chondrodysplasia calcificans punctata. BMJ Case Rep 2014;2014. pii: bcr2014205087.
  4. O'Brien TJ. Chondrodysplasia punctata (Conradi disease). Int J Dermatol 1990;29:472-6.
  5. Poznanski AK. Punctate epiphyses: A radiological sign not a disease. Pediatr Radiol 1994;24:418-24, 436.
  6. Kumar D, Babu TA, Aparna J. Rhizomelic chondrodysplasia punctata (RCDP): A case report. Curr Pediatr Res 2012;16:164-6.
  7. Sanfilippo A, Bartoletti S. Brachytelephalangic chondrodysplasia punctata: A difficult diagnosis. Radiol Case Rep 2010;5:308.
  8. White AL, Modaff P, Holland-Morris F, Pauli RM. Natural history of rhizomelic chondrodysplasia punctata. Am J Med Genet A 2003;118A: 332-42.
  9. Schweiger C, Nassar MN, Goebel D, Rutter MJ. Chondrodysplasia punctata presenting with tracheal obstruction. Int J Pediatr Otorhinolaryngol 2017;93:100-2.
  10. Wolpoe ME, Braverman N, Lin SY. Severe tracheobronchial stenosis in the X-linked recessive form of chondrodysplasia punctata. Arch Otolaryngol Head Neck Surg 2004;130:1423-6.
  11. Dewan P, Rai A, Gupta N, Shah D, Faridi MM. A rare lethal case of chondrodysplasia punctata with extensive airway involvement. Fetal Pediatr Pathol 2012;31:134-9.
  12. Karoutsos S, Lansade A, Terrier G, Mouliès D. Chondrodysplasia punctata and subglottic stenosis. Anesth Analg 1999;89:1322-3.
  13. Kaufmann HJ, Mahboubi S, Spackman TJ, Capitanio MA, Kirkpatrick J. Tracheal stenosis as a complication of chondrodysplasia punctata. Ann Radiol (Paris) 1976;19:203-9.
PDF Share
PDF Share

© Jaypee Brothers Medical Publishers (P) LTD.