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VOLUME 23 , ISSUE 11 ( November, 2019 ) > List of Articles
Abdul Rauf, Dhiren Gupta, Anil Sachdev, Suresh Gupta, Ramakant Sabharwal
Keywords : Congenital central hypoventilation, Electrical activity of diaphragm, Neurally adjusted ventilatory assist
Citation Information : Rauf A, Gupta D, Sachdev A, Gupta S, Sabharwal R. Neurally Adjusted Ventilatory Assist: An Early Clue to Diagnosis of Congenital Central Hypoventilation Syndrome. Indian J Crit Care Med 2019; 23 (11):536-537.
License: CC BY-NC 4.0
Published Online: 00-11-2019
Copyright Statement: Copyright © 2019; Jaypee Brothers Medical Publishers (P) Ltd.
Congenital central hypoventilation syndrome (CCHS) is characterized by shallow breathing during sleep due to negligible ventilatory sensitivity to hypercarbia and hypoxemia. It is diagnosed using a genetic test for PHOX2B mutation, which is not easily available. Neurally adjusted ventilatory assist (NAVA) is a spontaneous ventilatory mode that was designed basically for better adapting the ventilator to the patient by using electrical activity of diaphragm (EAdi) signals. We report a case of a 6-month-old infant who presented with recurrent apneas, where differential decrease in EAdi discharges during sleep using NAVA served as an early clue to the diagnosis of CCHS. Definitive diagnosis was later confirmed by genetic testing.
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