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VOLUME 23 , ISSUE 11 ( November, 2019 ) > List of Articles

LETTER TO THE EDITOR

Is There Any Lower Limit of Serum Bicarbonate in Diabetic Ketoacidosis?

Pragya Garg

Keywords : Diabetic ketoacidosis, High anion gap acidosis, Severe metabolic acidosis

Citation Information : Garg P. Is There Any Lower Limit of Serum Bicarbonate in Diabetic Ketoacidosis?. Indian J Crit Care Med 2019; 23 (11):542-542.

DOI: 10.5005/jp-journals-10071-23287

License: CC BY-NC 4.0

Published Online: 01-11-2019

Copyright Statement:  Copyright © 2019; Jaypee Brothers Medical Publishers (P) Ltd.


Abstract

Diabetic ketoacidosis (DKA) is known as one of the most serious complications of diabetes and associated with significant morbidity and mortality. It consists of a triad of uncontrolled hyperglycemia, metabolic acidosis, and increased total body ketone concentration.1 It leads to high anion gap metabolic acidosis with fall in serum bicarbonate.


  1. Kitabchi AE, Umpierrez GE, Miles JM, Fisher JN. Hyperglycemic crises in adult patients with diabetes. Diabetes Care 2009;32(7):1335–1343. DOI: 10.2337/dc09-9032.
  2. Kamarzaman Z, Turner C, Clark F. How low can you go: a case presentation on a patient with diabetic ketoacidosis. Resuscitation 2009;80(8):967–968. DOI: 10.1016/j.resuscitation.2009.05.007.
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