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VOLUME 23 , ISSUE 11 ( November, 2019 ) > List of Articles


Anisocoria: Realities, Recognition, and Remedial Aspects

Benita Florence, Ponniah Thirumalaikolundusubramanian

Keywords : Nebulization, Nebulizer, Palsy

Citation Information : Florence B, Thirumalaikolundusubramanian P. Anisocoria: Realities, Recognition, and Remedial Aspects. Indian J Crit Care Med 2019; 23 (11):543-543.

DOI: 10.5005/jp-journals-10071-23279

License: CC BY-NC 4.0

Published Online: 01-12-2019

Copyright Statement:  Copyright © 2019; The Author(s).


The realities, recognition, and remedial aspects of anisocoria at the bedside were highlighted by Adhikari et al.,1 which is almost similar to an earlier report from India.2 Since this condition involves patient safety and clinical assessment, we would like to touch upon 3 Ps (physiological, pathological, and pharmacological) of anisocoria. First and foremost is to elicit a thorough clinical history and then to assess the case in detail which not only rules out injuries, infections, instillation, or ingestion of medicines and instigating mechanisms but also helps rule out various other life-threatening conditions.

  1. Adhikari SD, Chakrabortty R, Kerai SI, Budoo MS. An elementary cause of aniscoria in intensive care unit. Indian J Crit Care Med 2019;23(7):346. DOI: 10.5005/jp-journals-10071-23213.
  2. SenthilKumaran S, Balamurugan N, Suresh P, Thirumalaikolundusubramanian P. Transient anisocoria: a pesky palpitation. J Neurosci Rural Pract 2011;2(2):210–211. DOI: 10.4103/0976-3147.83606.
  3. Senthilkumaran S, Balamurugan N, Menezes RG, Thirumalaikolundusubramanian P. Bedside test for anisocoria: not a small matter. Indian J Crit Care Med 2014;18(7):480–481. DOI: 10.4103/0972-5229.136084.
  4. Koc F, Kavuncu S, Kansu T, Acaroglu G, Firat E. The sensitivity and specificity of 0.5% aproclonidine in the diagnosis of oculosympathetic paresis. Br J Ophthalmol 2005;89(11):1442–1444. DOI: 10.1136/bjo.2005. 074492.
  5. Senthilkumaran S, Karthikeyan N, Jena NN, Florence B, Thirumalaikolundusubramanian P. Anisocoria and diagnostic application of pilocarpine—an eye opener. Am J Emerg Med 2019;37(8): 1586–1587. DOI: 10.1016/j.ajem.2019.05.029.
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