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VOLUME 23 , ISSUE 2 ( February, 2019 ) > List of Articles


Elizabethkingia Meningoseptica: An Emerging Nosocomial Pathogen Causing Septicemia in Critically Ill Patients

Manoj Kumar Sahu, Uma Balasubramaniam, C Bipin, Sarvesh Pal Singh, Sachin Talwar

Keywords : Elezabethkingia meningoseptica, Intensive care unit, Pediatric cardiac surgery, Sepsis

Citation Information : Sahu MK, Balasubramaniam U, Bipin C, Singh SP, Talwar S. Elizabethkingia Meningoseptica: An Emerging Nosocomial Pathogen Causing Septicemia in Critically Ill Patients. Indian J Crit Care Med 2019; 23 (2):104-105.

DOI: 10.5005/jp-journals-10071-23127

License: CC BY-NC 4.0

Published Online: 01-09-2018

Copyright Statement:  Copyright © 2019; The Author(s).


Elizabethkingia meningoseptica (E. meningoseptica), is an opportunistic Gram-negative bacteria, normally found in water and soil, notorious for causing nosocomial infections in extremes of ages and immunocompromised patients. It is now emerging as a serious nosocomial pathogen, intrinsically resistant to several commonly used antibiotics (e.g. beta-lactams, aminoglycosides, carbapenems and colistin etc. and a cause of high mortality in critically ill patients in intensive care units (ICUs). We report the first case of E. meningoseptica sepsis in a 5 month old child after open heart surgery for transposition of great arteries, initially on extracorporeal membrane oxygenation, then prolonged mechanical ventilation, with various invasive devices, inotropes and exposed to broad spectrum antibiotics in our ICU. The case highlights the potential risk factors responsible for E.meningoseptica sepsis. Its unusual pattern of resistance to many commonly used antibiotics makes this organism difficult to treat.

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  1. King EO. “Studies on a group of previously unclassified bacteria associated with meningitis in infants,” American Journal of Clinical Pathology.1959;31:241–247.
  2. Ceyhan M, Celik M. Elizabethkingia meningosepticum (Chryseobacterium meningosepticum) Infections in Children. Int J Pediatr. 2011; 215–237.
  3. Chiu CH, Waddingdon M et al. “Atypical Chryseobacterium meningosepticum and meningitis and sepsis in newborns and the immunocompromised, Taiwan,” Emerging Infectious Diseases. 2000; 6 (5): 481-486.
  4. Hoque SN, Graham J et al. “Chryseobacterium (Flavobacterium) meningosepticum outbreak associated with colonization of water taps in a neonatal intensive care unit,” Journal of Hospital Infection. 2001; 47(3):188-192.
  5. Nulens E, Bussels B et al. “Recurrent bacteremia by Chryseobacterium indologenes in an oncology patient with a totally implanted intravenous device,” Clinical Microbiology and Infection. 2001; 7(7);391-393.
  6. Lin PY, Chu C et al. Microbiological Analysis of Bloodstream Infections Caused by Chryseobacterium meningosepticum in Nonneonatal Patients. J Clin Microbiol. 2004; 42:3353-3355.
  7. Kirby JT, Sader HS et al. Antimicrobial Susceptibility and Epidemiology of a Worldwide Collection of Chryseobacterium spp.: Report from the SENTRY Antimicrobial Surveillance Program (1997–2001) J Clin Microbiol. 2004;42:445-448.
  8. Pereira GH, de Oliveira Garcia D et al. Nosocomial infections caused by Elizabethkingia Meningoseptica: An emerging pathogen. Braz J Infec Dis.2013;17:606-609.
  9. Güngör S, Özen M et al. “A Chryseobacteriummeningosepticum outbreak in a neonatal ward,” Infection Control and Hospital Epidemiology.2003; 24(8):613-617.
  10. Ratner H. “Flavobacterium meningosepticum,” Infection Control.1984; 5(5) 237-239.
  11. Fraser SL, Jorgensen JH. “Reappraisalof the antimicrobial susceptibilities of Chryseobacterium and Flavobacterium species and methods for reliable susceptibility testing,” Antimicrobial Agents and Chemotherapy. 1997; 12: 2738–2741.
  12. Govindaswamy A, Bajpai V, Trikha V, Mittal S, Malhotra R, Mathur P. Multidrug resistant Elizabethkingia meningoseptica bacteremia- Experience from a level 1 trauma centre in India. Intractable Rare Dis Res.2018;7(3):172-176.
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