Indian Journal of Critical Care Medicine

Register      Login



Volume / Issue

Online First

Related articles

VOLUME 23 , ISSUE 2 ( February, 2019 ) > List of Articles


Intravascular Hemolysis in Aluminium Phosphide Poisoning

Sayan Malakar, Bhagwan Dass Negi, Katyayani Dutt, Sujeet Raina

Keywords : Aluminum phosphide, Hemolysis, Intravascular, Poisoning

Citation Information : Malakar S, Negi BD, Dutt K, Raina S. Intravascular Hemolysis in Aluminium Phosphide Poisoning. Indian J Crit Care Med 2019; 23 (2):106-107.

DOI: 10.5005/jp-journals-10071-23128

License: CC BY-NC 4.0

Published Online: 01-09-2018

Copyright Statement:  Copyright © 2019; The Author(s).


Hemolysis associated with aluminum phosphide poisoning is very rare. Intravascular hemolysis in presence of glucose-6-phosphate dehydrogenase (G6PD) deficiency has been reported rarely in literature. We are reporting a case of young male patient with history of aluminum phosphide poisoning and complicated with intravascular hemolysis without G6PD deficiency. It has been reported only once in the literature.

PDF Share
  1. Shadnia S, Sasanian G et al. A retrospective 7-years study of aluminum phosphide poisoning in Tehran: Opportunities for prevention. Hum Exp Toxicol 2009;28:209-213.
  2. Farahani MV, Soroosh D et al. Thoughts on the current management of acute aluminum phosphide toxicity and proposals for therapy: An Evidence-based review. Indian J Crit Care Med 2016;20:724-730.
  3. Sood AK, Mahajan A et al. Intravascular hemolysis after aluminum phosphide ingestion. J R Soc Med. 1997;90:47
  4. Srinivas R, Agarwal R et al. Intravascular haemolysis due to glucose6phosphate dehydrogenase deficiency in a patient with aluminum phosphide poisoning. Emerg Med J 2007;24:678.
  5. Aggarwal P, Handa R et al. Intravascular hemolysis in aluminum phosphide poisoning. Am J Emerg Med 1999; 17:488–489.
  6. Chin KL, Mai X et al. The interaction of phosphine with hemoglobin and erythrocytes. Xenobiotica 1992; 22:599–607.
  7. Rahimi N, Abdolghaffari AH et al. Fresh red blood cells transfusion protects against aluminum phosphide-induced metabolic acidosis and mortality in rats. PLoS ONE 2018; 13: e0193991.
PDF Share
PDF Share

© Jaypee Brothers Medical Publishers (P) LTD.