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VOLUME 23 , ISSUE 6 ( June, 2019 ) > List of Articles

LETTER TO THE EDITOR

Colistin for Treatment of Multidrug Resistant Central Nervous System Infection: A Triple Route Therapy!

Ratnesh Kumar Shukla

Citation Information : Shukla RK. Colistin for Treatment of Multidrug Resistant Central Nervous System Infection: A Triple Route Therapy!. Indian J Crit Care Med 2019; 23 (6):287-287.

DOI: 10.5005/jp-journals-10071-23183

License: CC BY-NC 4.0

Published Online: 01-06-2019

Copyright Statement:  Copyright © 2019; Jaypee Brothers Medical Publishers (P) Ltd.


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  1. Imberti R, Iotti GA, Regazzi M. Intraventricular or intrathecal colistin for the treatment of central nervous system infection caused by multidrug-resistant Gram-negative bacteria. Expert Rev Anti Infect Ther. 2014;12:471–478. doi: 10.1586/14787210.2014.896740
  2. Bargiacchi O, Rossati A, Car P, Brustia D, Brondolo R, Rosa F, et al. Intrathecal/intraventricular colistin in external ventricular device-related infections by multi-drug resistant Gram negative bacteria: case reports and review. Infection. 2014;42:801–809. doi: 10.1007/s15010-014-0618-0
  3. Karaiskos I, Galani L, Baziaka F, Katsouda E, Ioannidis I, Andreou A, et al. Successful treatment of extensively drug-resistant Acinetobacter baumannii ventriculitis and meningitis with intraventricular colistin after application of a loading dose: a case series. Int J Antimicrob Agents. 2013;41:480–483. doi: 10.1016/j.ijantimicag.2013.02.010
  4. Ziaka M, Markantonis SL, Fousteri M, Zygoulis P, Panidis D, Karvouniaris M, et al. Combined intravenous and intraventricular administration of colistin methanesulfonate in critically ill patients with central nervous system infection. Antimicrob Agents Chemother. 2013;57:1938–1940. doi: 10.1128/AAC.01461-12
  5. Karaiskos I, Galani L, Baziaka F, Giamarellou H. Intraventricular and intrathecal colistin as the lasttherapeutic resort for the treatment of multidrug-resistant and extensively drug-resistant Acinetobacter baumannii ventriculitis and meningitis: a literature review. Int J Antimicrob Agents. 2013;41:499–508. doi: 10.1016/j.ijantimicag.2013.02.006
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