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VOLUME 23 , ISSUE 8 ( August, 2019 ) > List of Articles

Original Article

Spectrum and Immediate Outcome of Acute Kidney Injury in a Pediatric Intensive Care Unit: A Snapshot Study from Indian Subcontinent

Ashwini Bharat, Anita Mehta, Harish Chandra Tiwari, Bhupendra Sharma

Keywords : Acute kidney injury (AKI), Pediatric intensive care unit (PICU), pRIFLE, Viral encephalitis, Scrub typhus

Citation Information : Bharat A, Mehta A, Tiwari HC, Sharma B. Spectrum and Immediate Outcome of Acute Kidney Injury in a Pediatric Intensive Care Unit: A Snapshot Study from Indian Subcontinent. Indian J Crit Care Med 2019; 23 (8):352-355.

DOI: 10.5005/jp-journals-10071-23217

License: CC BY-NC 4.0

Published Online: 01-08-2019

Copyright Statement:  Copyright © 2019; Jaypee Brothers Medical Publishers (P) Ltd.


Abstract

Background and aims: Acute kidney injury (AKI) became an important cause of mortality and morbidity in critically ill children, despite advancement in its management. In developing countries etiology of AKI are different from that of developed countries. Materials and methods: This observational study was carried out in pediatric intensive care unit (PICU) in 2 months to 18 years of critically ill children. Kidney injury was defined and categorized by the pRIFLE criteria. Results: Out of 361children, 86 children (23.8%) developed AKI at some point during admission, 275 children (age and sex matched) who did not develop kidney injury during hospitalization served as non-AKI children. Maximum cases of AKI were seen in 1–5 years of age. Maximum children of AKI were of viral encephalitis (n = 43, 50.0%) followed by scrub typhus (n = 14, 16.3%). Risk factors for the development of AKI were shock, PRISM score and longer hospital stay. In our study the mortality in AKI children (n = 30, 34.8%) was significantly higher (p = 0.005) as compared to non-AKI children (n = 56, 20.3%)). Duration on mechanical ventilation, PICU stay and hospital stay were also significantly (p = 0.001) higher in AKI children. Conclusion: AKI is common in critically ill children and associated with high mortality and morbidity.


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