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VOLUME 23 , ISSUE 8 ( August, 2019 ) > List of Articles

CASE REPORT

Serotonin Syndrome in ICU—A Road Less Traveled

Swati Jindal, Satinder Gombar

Keywords : Agitation, ICU, SSRI, Serotonin syndrome

Citation Information : Jindal S, Gombar S. Serotonin Syndrome in ICU—A Road Less Traveled. Indian J Crit Care Med 2019; 23 (8):376-377.

DOI: 10.5005/jp-journals-10071-23222

License: CC BY-NC 4.0

Published Online: 01-04-2019

Copyright Statement:  Copyright © 2019; The Author(s).


Abstract

A potentially life-threatening adverse drug reaction, serotonin syndrome (SS) may occur in patients on serotonin agonist medications. Medications responsible for SS include commonly prescribed antidepressants, anxiolytics, analgesics and antiemetics. This syndrome has been mentioned in various scenarios in perioperative setting but rarely acknowledged in intensive care unit (ICU) setting. Multiple comorbities leading to polypharmacy and serotoninergic medications place elderly patients, particularly at higher risk of SS. We wish to report a case of SS in an elderly male with depression who developed SS and required ICU admission. Most crucial point is to be able to recognize this entity whenever a patient on multiple drugs with altered sensorium is admitted to ICU.


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  1. Altman C, Jahangiri M. Serotonin Syndrome in the Perioperative Period. Anesth & Analg 2010;110:526–528.
  2. Pedavally S, Fugate J, Rabinstein A. Serotonin Syndrome in the Intensive Care Unit: Clinical Presentations and Precipitating Medications. Neurocritical Care 2013;21:108–113.
  3. Cooper B, Sejnowski C. Serotonin Syndrome. AACN Adv Crit Care 2013;24:15–20.
  4. Abstracts 2017. Can J Anaesth 2017;64(S1):261–266.
  5. Boyer, E. and Shannon, M. The Serotonin Syndrome. N Engl J Med 2005;352:1112–1120.
  6. Prakash S, Rathore C. Serotonin syndrome presenting as surgical emergency: A report of two cases. Indian J Crit Care Med 2016;20:120.
  7. Schuch L, Yip A, Nouri K, Gregersen M, Cason B, Kukreja J et al. Serotonin Syndrome Following an Uncomplicated Orthopedic Surgery in a Patient With Post-Traumatic Stress Disorder. Mil Med 2016;181:e1185–1188.
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