Blood transfusions are one of the most commonly prescribed interventions in the critically ill patients. Apart from being a life saving intervention, they can also be associated with life threatening complications. Despite multiple trials and guidelines, there is a wide variability and lack of adherence to the guideline\'s. Auditing transfusion practices help us in introspecting and modifying our prescriptions as per the recommended standards.
Sakr Y, Vincent JL. Should red cell transfusion be individualized? Yes. Intensive Care Med. 2015;41:1973–1976.
Rohde JM, Dimcheff DE, Blumberg N, Saint S, Langa KM, Kuhn L, et al. Health care-associated infection after red blood cell transfusion: a systematic review and meta-analysis. JAMA. 2014;311:1317–1326.
Gilliland CT, Sittampalam GS, Wang PY, Ryan PE. The translational science-training program at NIH: introducing early career researchers to the science and operation of translation of basic research to medical interventions. Biochemistry and Molecular Biology Education 2017;45:13–24.
Morris ZS, Wooding S, Grant J. The answer is 17 years, what is the question: understanding time lags in translational research. Journal of the Royal Society of Medicine 2011;104:510–520.
Cooksey D. A review of UK health research funding, 2006. https://www.gov.uk/government/uploads/system/uploads/attachment data/file/228984/0118404881.pdf (accessed 06/11/2016).
Corwin HL, Gettinger A, Pearl RG, Fink MP, Levy MM, Abraham E, et al. The CRIT Study: anemia and blood transfusion in the critically ill – Current clinical practice in the United States. Critical Care Medicine 2004;32:39–52.
Vincent JL, Baron JF, Reinhart K, Gattinoni L, Thijs L, Webb A, et al. Anemia and blood transfusion in critically ill patients. Journal of the American Medical Association 2002;288:1499–1507.
Cabana MD, Rand CS, Powe NR, Wu AW, Wilson MH, Abboud PA, et al. Why don't physicians follow clinical practice guidelines? A framework for improvement. JAMA 1999;282:1458–1465.
Astrid Norgaard, Trine Honnens de Lichtenberg, Jens Nielsen, Pär I Johansson. Monitoring compliance with transfusion guidelines in hospital departments by electronic data capture. Blood Transfus 2014;12:509–519.
Bolton-Maggs, PHB and Cohen, H. (2013) Serious hazards of transfusion (SHOT) haemovigilance and progress is improving transfusion safety. Br J Haemalot, 163, 303–314.
Resar R, Griffin FA, Haraden C, Nolan TW. Using Care Bundles to Improve Health Care Quality. IHI Innovation Series white paper. Cambridge, Massachusetts: Institute for Healthcare Improvement, 2012. www.ihi.org/resources/Pages/IHIWhitePapers/UsingCareBundles.aspx (23 June 2015, date last accessed).
Berenholtz SM, Pronovost PJ, Lipsett PA, Hobson D, Earsing K, Farley JE, et al. Eliminating catheterrelated bloodstream infections in the intensive care unit. Crit Care Med 2004;32:2014–2020.
Peter Pronovost, Dale Needham, Sean Berenholtz, David Sinopoli, Haitao Chu, Sara Cosgrove, et al. An intervention to decrease catheter-related bloodstream infections in the ICU. N Engl J Med 2006;355:2725–2732.
Borgert M, Binnekade J, Paulus F, Vroom M, Vlaar A, Goossens A, et al. Implementation of a transfusion bundle reduces inappropriate red blood cell transfusions in intensive care - a before and after study. Transfus Med. 2016 Dec;26(6):432-439. doi: 10.1111/tme.12364. Epub 2016 Oct 11.
Borgert M, Binnekade J, Paulus F, Goossens A, Vroom M, Dongelmans D. Timely individual audit and feedback significantly improves transfusion bundle compliance-a comparative study. Int J Qual Health Care. 2016 Oct;28(5):601-607. Epub 2016 Jul 15