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VOLUME 24 , ISSUE 7 ( July, 2020 ) > List of Articles

Original Article

Health-related Quality of Life Evaluated by MOS SF-36 in the Elderly Patients 1 Month before ICU Admission and 3 Months after ICU Discharge

Zineb Zeggwagh, Khalid Abidi, Mohamed NZ Kettani, Amina Iraqi, Tarek Dendane, Amine Ali Zeggwagh

Keywords : Elderly, Intensive care unit, MOS SF36, Quality of life

Citation Information : Zeggwagh Z, Abidi K, Kettani MN, Iraqi A, Dendane T, Zeggwagh AA. Health-related Quality of Life Evaluated by MOS SF-36 in the Elderly Patients 1 Month before ICU Admission and 3 Months after ICU Discharge. Indian J Crit Care Med 2020; 24 (7):531-538.

DOI: 10.5005/jp-journals-10071-23489

License: CC BY-NC 4.0

Published Online: 05-09-2020

Copyright Statement:  Copyright © 2020; Jaypee Brothers Medical Publishers (P) Ltd.


Abstract

Objectives: The aims of this study were to evaluate changes in health-related quality of life (HRQoL) before ICU admission and after ICU discharge in elderly patients and to determine predictors of this HRQoL. Materials and methods: This prospective study has been realized in the medical ICU (August 2012-March 2013). All patients 65 years of age or older who were hospitalized for ≥48 hours in our medical ICU have been included. The HRQoL was assessed 1 month prior to ICU admission in all the patients at admission and 3 months after ICU discharge for survivors using the Arabic version of MOS SF-36 questionnaire. Results: We enrolled 118 patients (66 M: 55.9% and 52 F: 44.1%). The mean age was 72 ± 6 years. ICU mortality rate was 47.5% and three-month mortality rate was 55.1%. The reliability and validity of MOS SF-36 were satisfactory. Among the 53 survivors at follow-up, the subscales of MOS SF-36 decreased significantly at 3 months after ICU stay except the “Bodily Pain”. The physical component score (PCS) and mental component score (MCS) decreased also significantly. The independent factors strongly associated with PCS and its variations were: age (β = −1.56, p = 0.001), prior functional status (β = −22.10, p = 0.002) and SAPSII (β = −0.16, p = 0.04). For MCS, these factors were: live alone (β = 16.50, p = 0.006), previous functional status (β = −9.09, p = 0.008) and existence of education level (β = 2.98, p = 0.037). Conclusion: We demonstrated a fall in the physical and psychical aspects of HRQoL 3 months after ICU discharge in the elderly patients. In addition to factors such as age, prior functional status and severity of illness, family status and educational level seem decisive in the post-ICU HRQoL.


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  1. Azoulay E, Kentish-Barnes N, Pochard F. Health-related quality of life: an outcome variable in critical care survivors. Chest 2008;133(2):339–341. DOI: 10.1378/chest.07-2547.
  2. Khouli H, Astua A, Dombrowski W, Ahmad F, Homel P, Shapiro J, et al. Changes in health-related quality of life and factors predicting long-term outcomes in older adults admitted to intensive care units. Crit Care Med 2011;39(4):731–737. DOI: 10.1097/CCM.0b013e318208edf8.
  3. Mafra JM, Maria da Silva J, Yamada da Silveira LT, Fu C, Tanaka C. Quality of life of critically ill patients in a developing country: a prospective longitudinal study. J Phys Ther Sci 2016;28(10):2915–2920. DOI: 10.1589/jpts.28.2915.
  4. Kaarlola A, Tallgren M, Pettilä V. Long-term survival, quality of life and quality adjusted life-years among critically ill elderly patients. Crit Care Med 2006;34(8):2120–2126. DOI: 10.1097/01.CCM.0000227656.31911.2E.
  5. Viricel L, Auboyer C, Sauron C, Mathern P, Gonthier R. Devenir et qualité de vie d'une population âgée de plus de 80 ans trois mois après un séjour en réanimation. Ann Readapt Med Phys 2007;50(7):590–599. DOI: 10.1016/j.annrmp.2007.03.015.
  6. Khoudri I, Zeggwagh AA, Abidi K, Madani N, Abouqal R. Measurement properties of the short form 36 and health-related quality of life after intensive care in Morocco. Acta Anaesthesiol Scand 2007;51(2):189–197. DOI: 10.1111/j.1399-6576.2006.01225.x.
  7. Khoudri I, Belayachi J, Dendane T, Abidi K, Madani N, Zekraoui A, et al. Measuring quality of life after intensive care using the Arabic version for Morocco of the EuroQol 5 dimensions. BMC Res Notes 2012;5(1):56. DOI: 10.1186/1756-0500-5-56.
  8. Leplège A, Ecosse E, Pouchot J, Coste J, Perneger T. Le questionnaire MOS SF-36. Manuel de l'utilisateur et guide d'interprétation des scores. Paris: Éditions ESTEM; 2001. p. 156.
  9. Chrispin PS, Scotton H, Rogers J, Lloyd D, Ridley SA. Short form 36 in the intensive care unit: assessment of acceptability, reliability and validity of the questionnaire. Anaesthesia 1997;52(1):15–23. DOI: 10.1111/j.1365-2044.1997.015-az014.x.
  10. Capuzzo M, Grasselli C, Carrer S, Gritti G, Alvisi R. Quality of life before intensive care admission: agreement between patient and relative assessment. Intensive Care Med 2000;26(9):1288–1295. DOI: 10.1007/s001340051341.
  11. Hofhuis J, Hautvast JL, Schrijvers AJ, Bakker J. Quality of life on admission to the intensive care: can we query the relatives? Intensive Care Med 2003;29(6):974–979. DOI: 10.1007/s00134-003-1763-6.
  12. Carr AJ, Gibson B, Robinson PG. Is quality of life determined by expectations or experience? BMJ 2001;322(7296):1240–1243. DOI: 10.1136/bmj.322.7296.1240.
  13. Iwashyna TJ, Netzer G. The burdens of survivorship: an approach to thinking about long-term outcomes after critical illness. Semin Respir Crit Care Med 2012;33(4):327–328. DOI: 10.1055/s-0032-1321982.
  14. Konopad E, Noseworthy TW, Johnston R, Shustack A, Grace M. Quality of life measures before and one year after admission to an intensive care unit. Crit Care Med 1995;23(10):1653–1659. DOI: 10.1097/00003246-199510000-00008.
  15. Udekwu P, Gurkin B, Oller D, Lapio L, Bourbina J. Quality of life and functional level in elderly patients surviving surgical intensive care. J Am Coll Surg 2001;193(3):245–249. DOI: 10.1016/s1072-7515(01)00994-2.
  16. de Rooij SE, Govers AC, Korevaar JC, Giesbers AW, Levi M, de Jonge E. Cognitive, functional and quality of life outcomes of patients aged 80 and older who survived at least 1 year after planned or unplanned surgery or medical intensive care treatment. J Am Geriatr Soc 2008;56(5):816–822. DOI: 10.1111/j.1532-5415.2008.01671.x.
  17. Orwelius L, Fredrikson M, Kristenson M, Walther S, Sjöberg F. Health-related quality of life scores after intensive care are almost equal to those of the normal population: a multicenter observational study. Crit Care 2013;17(5):R236. DOI: 10.1186/cc13059.
  18. Rogers J, Ridley S, Chrispin P, Scotton H, Lloyd D. Reliability of the next of kins'estimates of critically ill patients'quality of life. Anaesthesia 1997;52(12):1137–1143. DOI: 10.1111/j.1365-2044.1997.240-az0374.x.
  19. Pierre U, Wood-Dauphinee S, Korner-Bitensky N, Gayton D, Hanley J. Proxy use of the Canadian SF-36 in rating health status of the disabled elderly. J Clin Epidemiol 1998;51(11):983–990. DOI: 10.1016/s0895-4356(98)00090-0.
  20. Graf J, Koch M, Dujardin R, Kersten A, Janssens U. Health-related quality of life before, 1 month after, and 9 months after intensive care in medical cardiovascular and pulmonary patients. Crit Care Med 2003;31(8):2163–2169. DOI: 10.1097/01.CCM.0000079607.87009.3A.
  21. Chelluri L, Pinsky MR, Donahoe MP, Grenvik A. Long-term outcome of critically ill elderly patients requiring intensive care. JAMA 1993;269(24):3119–3123. DOI: 10.1001/jama.1993.03500240063027.
  22. Montuclard L, Garrouste-Orgeas M, Timsit JF, Misset B, de Jonghe B, Carlet J. Outcome, functional autonomy and quality of life of elderly patients with a long-term intensive care unit stay. Crit Care Med 2000;28(10):3389–3395. DOI: 10.1097/00003246-200010000-00002.
  23. Hennessy D, Juzwishin K, Yergens D, Noseworthy T, Doig C. Outcomes of elderly survivors of intensive care. A review of the literature. Chest 2005;127(5):1764–1774. DOI: 10.1378/chest.127.5.1764.
  24. Angus DC, Carlet J. Surviving intensive care: a report from the 2002 Brussels Roundtable. Intensive Care Med 2003;29(3):368–377. DOI: 10.1007/s00134-002-1624-8.
  25. Hofhuis JG, Spronk PE, van Stel HF, Schrijvers GJ, Rommes JH, Bakker J. The impact of critical illness on perceived health-related quality of life during ICU treatment, hospital stay, and after hospital discharge: a longterm follow-up study. Chest 2008;133(2):377–385. DOI: 10.1378/chest.07-1217.
  26. Tabah A, Philippart F, Timsit J, Willems V, Français A, Leplège A, et al. Quality of life in patients aged 80 or over after ICU discharge. Crit Care 2010;14(1):R2. DOI: 10.1186/cc8231.
  27. Vest MT, Murphy TE, Araujo KL, Pisani MA. Disability in activities of daily living, depression, and quality of life among older medical ICU survivors: a prospective cohort study. Health Qual Life Outcomes 2011;9(1):9. DOI: 10.1186/1477-7525-9-9.
  28. Garrouste-Orgeas M, Timsit JF, Montuclard L, Colvez A, Gattolliat O, Philippart F, et al. Decision-making process, outcome, and 1-year quality of life of octogenarians referred for intensive care unit admission. Intensive Care Med 2006;32(7):1045–1051. DOI: 10.1007/s00134-006-0169-7.
  29. Rellos K, Falagas ME, Vardakas KZ, Sermaides G, Michalopoulos A. Outcome of critically ill oldest-old patients (aged 90 and older) admitted to the intensive care unit. J Am Geriatr Soc 2006;54(1):110–114. DOI: 10.1111/j.1532-5415.2005.00544.x.
  30. Welsh CH, Thompson K, Long-Krug S. Evaluation of patient-perceived health status using the medical outcome survey short-form 36 in an intensive care unit population. Crit Care Med 1999;27(8):1466–1471. DOI: 10.1097/00003246-199908000-00011.
  31. Orwelius L, Nordlund A, Nordlund P, Simonsson E, Bäckman C, Samuelsson A, et al. Pre-existing disease: the most important factor for health related quality of life long-term after critical illness: a prospective, longitudinal, multicentre trial. Crit Care 2010;14(2):R67. DOI: 10.1186/cc8967.
  32. Oeyen SG, Vandijck DM, Benoit DD, Annemans L, Decruyenaere JM. Quality of life after intensive care: A systematic review of the literature. Crit Care Med 2010;38(12):2386–2400. DOI: 10.1097/CCM.0b013e3181f3dec5.
  33. Dowdy DW, Eid MP, Sedrakyan A, Mendez-Tellez PA, Pronovost PJ, Herridge MS, et al. Quality of life in adult survivors of critical illness: a systematic review of the literature. Intensive Care Med 2005;31(5):611–620. DOI: 10.1007/s00134-005-2592-6.
  34. Jeitziner MM, Zwakhalen SM, Bürgin R, Hantikainen V, Hamers JP. Changes in health-related quality of life in older patients one year after an intensive care unit stay. J Clin Nurs 2015;24(21-22):3107–3117. DOI: 10.1111/jocn.12904.
  35. Schelling G, Stoll C, Haller M, Briegel J, Manert W, Hummel T, et al. Health-related quality of life and posttraumatic stress disorder in survivors of the acute respiratory distress syndrome. Crit Care Med 1998;26(4):651–659. DOI: 10.1097/00003246-199804000-00011.
  36. Cox CE, Carson SS, Lindquist JH, Olsen MK, Govert JA, Chelluri L, et al. Differences in one-year health outcomes and resource utilization by definition of prolonged mechanical ventilation: a prospective cohort study. Crit Care 2007;11(1):R9. DOI: 10.1186/cc5667.
  37. Morsch C, Thomé FS, Balbinotto A, Guimarães JF, Barros EG. Health-related quality of life and dialysis dependence in critically ill patient survivors of acute kidney injury. Ren Fail 2011;33(10):949–956. DOI: 10.3109/0886022X.2011.615966.
  38. Quispe-Laime AM, Fiore C, González-Ros MN, Bettini JE, Rolfo VE, Campagne CG, et al. Lung diffusion capacity and quality of life 6 months after discharge from the ICU among survivors of acute respiratory distress syndrome due to influenza A H1N1. Med Intensiva 2012;36(1):15–23. DOI: 10.1016/j.medin.2011.09.007.
  39. Contrin LM, Paschoal VD, Beccaria LM, Cesarino CB, Lobo SM. Quality of life of severe sepsis survivors after hospital discharge. Rev Lat Am Enfermagem 2013;21(3):795–802. DOI: 10.1590/S0104-11692013000300020.
  40. Fakhry SM, Kercher KW, Rutledge R. Survival, quality of life, and changes in critically ill surgical patients requiring prolonged ICU stays. J Trauma 1996;41(6):999–1007. DOI: 10.1097/00005373-199612000-00010.
  41. Wehler M, Martus P, Geise A, Bost A, Mueller A, Hahn EG, et al. Changes in quality of life after medical intensive care. Intensive Care Med 2001;27(1):154–159. DOI: 10.1007/s001340000769.
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