Indian Journal of Critical Care Medicine

Register      Login



Volume / Issue

Online First

Related articles

VOLUME 24 , ISSUE 7 ( July, 2020 ) > List of Articles


Sevoflurane Sedation with AnaConDa-S Device for a Child Undergoing Extracorporeal Membrane Oxygenation

Yohan Soreze, Jean-Eudes Piloquet, Alain Amblard, Isabelle Constant, Jerome Rambaud, Pierre-Louis Léger

Citation Information : Soreze Y, Piloquet J, Amblard A, Constant I, Rambaud J, Léger P. Sevoflurane Sedation with AnaConDa-S Device for a Child Undergoing Extracorporeal Membrane Oxygenation. Indian J Crit Care Med 2020; 24 (7):596-598.

DOI: 10.5005/jp-journals-10071-23487

License: CC BY-NC 4.0

Published Online: 22-11-2020

Copyright Statement:  Copyright © 2020; The Author(s).


Background: Deep sedation in critically ill children undergoing extracorporeal membrane oxygenation (ECMO) can be challenging. Volatile anesthetics like sevoflurane can be a good alternative for patients hospitalized in pediatric intensive care units, in whom adequate sedation is difficult to obtain. Case description: We report here the first pediatric case of a patient under extracorporeal membrane oxygenation receiving sedation by sevoflurane using the AnaConDa-S device. This 2-year-old girl, suffering from congenital diaphragmatic hernia, was put on extracorporeal membrane oxygenation due to a persistent pulmonary hypertension following metapneumovirus infection. Despite high doses of drugs, neither satisfactory sedation nor analgesia could be reached. Sevoflurane allowed her to be released and we were able to wean her from certain drugs. Her physiological parameters and the indicators of pain and sedation improved. Conclusion: Anesthesia using sevoflurane with the AnaConDa-S device is efficient for children under ECMO. Clinical significance: This is the first pediatric report on anesthesia with sevoflurane under ECMO.

  1. Sackey PV, Martling C-R, Radell PJ. Three cases of PICU sedation with isoflurane delivered by the “AnaConDa”. Paediatr Anaesth 2005;15(10):879–885.
  2. Meiser A, Bomberg H, Lepper PM, Trudzinski FC, Volk T, Groesdonk HV. Inhaled sedation in patients with acute respiratory distress syndrome undergoing extracorporeal membrane oxygenation. Anesth Analg 2017;125(4):1235–1239.
  3. Jevtovic-Todorovic V. General anesthetics and neurotoxicity: How much do we know? Anesthesiol Clin 2016;34(3):439–451.
  4. Murphy KL, McGaughy J, Croxson PL, Baxter MG. Exposure to sevoflurane anesthesia during development does not impair aspects of attention during adulthood in rats. Neurotoxicol Teratol 2017;60:87–94.
  5. Jiang J, Tang C, Ren J, Zhang C, Dong L, Zhu Z. Effect of multiple neonatal sevoflurane exposures on hippocampal apolipoprotein E levels and learning and memory abilities. Pediatr Neonatol 2018;59(2):154–160.
PDF Share
PDF Share

© Jaypee Brothers Medical Publishers (P) LTD.