Indian Journal of Critical Care Medicine

Register      Login



Volume / Issue

Online First

Related articles

VOLUME 25 , ISSUE 3 ( March, 2021 ) > List of Articles


Does Presence of Sepsis by Itself Predispose the Patients to HCAIs?

Sheetal Gaikwad

Citation Information : Gaikwad S. Does Presence of Sepsis by Itself Predispose the Patients to HCAIs?. Indian J Crit Care Med 2021; 25 (3):253-254.

DOI: 10.5005/jp-journals-10071-23771

License: CC BY-NC 4.0

Published Online: 01-05-2021

Copyright Statement:  Copyright © 2021; The Author(s).


  1. Chintamani A, Prakash B, Abraham BK, Kumar S, Ramakrishnan N, Venkataraman R. Incidence and impact of healthcare-associated infections on patients primarily admitted with sepsis and non-sepsis diagnoses. Indian J Crit Care Med 2021;25(3):292–295.
  2. World Health Organization. Report on the burden of endemic health care-associated infection worldwide; 2011.
  3. Van Vught LA, Klein Klouwenberg PMC, Spitoni C, Scicluna BP, Wiewel MA, Horn J, et al. Incidence, risk factors, and attributable mortality of secondary infections in the intensive care unit after admission for sepsis. JAMA 2016;315(14):1469–1479. DOI: 10.1001/jama.2016.2691.
  4. Hotchkis RS, Monneret G, Payen D. Immunosuppression in sepsis: a novel understanding of the disorder and a new therapeutic approach. Lancet Infect Dis 2013;13(3):260–268. DOI: 10.1016/S1473-3099(13)70001-X.
  5. Frazier WJ, Hall MW. Immunoparalysis and adverse outcomes from critical illness. Pediatr Clin North Am 2008;55(3):647–668, xi. DOI: 10.1016/j.pcl.2008.02.009.
  6. Polk HC Jr, George CD, Wellhausen SR, Cost K, Davidson PR, Regan MP, et al. A systematic study of host defense processes in badly injured patients. Ann Surg 1986;204(3):282–299.
  7. Stolk RF, van der Poll T, Angus DC, van der Hoeven JG, Pickkers P, Kox M. Potentially inadvertent immunomodulation: norepinephrine use in sepsis. Am J Respir Crit Care Med 2016;194(5):550–558. DOI: 10.1164/rccm.201604-0862CP.
  8. Le Tulzo Y, Pangault C, Amiot L, Guilloux V, Tribut O, Arvieux C, et al. Monocyte human leukocyte antigen-DR transcriptional downregulation by cortisol during septic shock. Am J Respir Crit Care Med 2004;169(10):1144–1151. DOI: 10.1164/rccm.200309-1329OC.
  9. Digiovine B, Chenoweth C, Watts C, Higgins M. The attributable mortality and costs of primary nosocomial bloodstream infections in the intensive care unit. Am J Respir Crit Care Med 1999;160(3):976–981. DOI: 10.1164/ajrccm.160.3.9808145.
  10. Mesiano ER, Merchán-Hamann E. Bloodstream infections among patients using central venous catheters in intensive care units. Rev Lat Am Enfermagem 2007;15(3):453–459. DOI: 10.1590/s0104-11692007000300014.
  11. Girou E, Stephan F, Novara A, Safar M, Fagon JY. Risk factors and outcome of nosocomial infections: results of a matched case-control study of ICU patients. Am J Respir Crit Care Med 1998;157(4):1151–1158. DOI: 10.1164/ajrccm.157.4.9701129.
PDF Share
PDF Share

© Jaypee Brothers Medical Publishers (P) LTD.