Melioidosis in a Tertiary Care Center from South India: A 5-year Experience
Mariappan Murugan, Raja Sundaramurthy, Geni VG Soundaram
Citation Information :
Murugan M, Sundaramurthy R, Soundaram GV. Melioidosis in a Tertiary Care Center from South India: A 5-year Experience. Indian J Crit Care Med 2021; 25 (3):327-330.
The present study was done with the objective to know the clinical presentation, microbiological features, and treatment outcome of melioidosis patients in our hospital, which is an emerging infection in India, and to know the differences in clinical course and outcome between bacteremic and nonbacteremic patients. This retrospective observational study was carried out over a period of 5 years from January 2015 to December 2019. Thirty-five cases of culture-confirmed melioidosis were identified with age range between 5 and 74 years. A large number of patients (n = 31) presented with uncontrolled diabetes mellitus. Six patients died of septic shock, and the outcome of eight patients was unknown as they were discharged against medical advice. There were no relapses observed. Melioidosis growing as a neglected tropical disease in India warrants awareness among all clinicians across the country.
Vijaykumar GS, Thilakavathy P, Jeremiah SS, Vithiya G. Osteomyelitis of humerus and intramuscular abscess due to melioidosis. Kathmandu Univ Med J 2016;14(54):184–185. PMID: 28166079.
Ganesan V, Sundaramoorthy R, Subramanian S. Melioidosis-series of seven cases from Madurai, Tamil Nadu, India. Indian J Crit Care Med 2019;23(3):149–151. DOI: 10.5005/jp-journals-10071-23139.
Mukhopadhyay C, Shaw T, Varghese GM, Dance DAB. Melioidosis in South Asia (India, Nepal, Pakistan, Bhutan and Afghanistan). Trop Med Infect Dis 2018;3(2):51. DOI: 10.3390/tropicalmed3020051.
Koshy M, Jagannati M, Ralph R, Victor P, David T, Sathyendra S, et al. Clinical manifestations, antimicrobial drug susceptibility patterns, and outcomes in melioidosis cases, India. Emerg Infect Dis 2019;25(2):316–320. DOI: 10.3201/eid2502.170745.
Wongwandee M, Linasmita P. Central nervous system melioidosis: a systematic review of individual participant data of case reports and case series. PLoS Negl Trop Dis 2019;13(4):e0007320. DOI: 10.1371/journal.pntd.0007320.
Prasad GL, Nair RP, Menon GR. Intracranial melioidosis: First report in a human immunodeficiency virus positive individual manifesting as cranial osteomyelitis. Neurol India 2017;65(6):1423–1426. DOI: 10.4103/0028-3886.217952.
