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VOLUME 25 , ISSUE 3 ( March, 2021 ) > List of Articles

LETTER TO EDITOR

Phenytoin Sodium and Acetate–Maleate Buffered Balanced Salt Solutions are Physically Incompatible!

Charu Mahajan, Brijesh P Singh, Indu Kapoor

Keywords : Balanced salt solutions, Incompatibility, Phenytoin

Citation Information : Mahajan C, Singh BP, Kapoor I. Phenytoin Sodium and Acetate–Maleate Buffered Balanced Salt Solutions are Physically Incompatible!. Indian J Crit Care Med 2021; 25 (3):352-352.

DOI: 10.5005/jp-journals-10071-23756

License: CC BY-NC 4.0

Published Online: 20-03-2021

Copyright Statement:  Copyright © 2021; Jaypee Brothers Medical Publishers (P) Ltd.


Abstract


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  1. Hafizah M, Liu CY, Ooi JS. Normal saline versus balanced-salt solution as intravenous fluid therapy during neurosurgery: effects on acid-base balance and electrolytes. J Neurosurg Sci 2017;61(3):263–270. DOI: 10.23736/S0390-5616.16.03221-5.
  2. Onuki Y, Ikegami-Kawai M, Ishitsuka K, Hyashi Y, Takayama K. A 5% glucose infusion fluid provokes significant precipitation of phenytoin sodium injection via interruption of the cosolvent effect of propylene glycol. Chem Pharm Bull (Tokyo) 2012;60(1):86–93. DOI: 10.1248/cpb.60.86.
  3. Heiderich S, Jürgens J, Rudolf D, Dennhardt N, Echtermeyer F, Leffler A, et al. Compatibility of common drugs with acetate-containing balanced electrolyte solutions in pediatric anesthesia. Paediatr Anaesth 2016;26(6):590–598. DOI: 10.1111/pan.12889.
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