Citation Information :
Davari H, Ebrahimian A, Rezayei S, Tourdeh M. Effect of Lavender Aromatherapy on Sleep Quality and Physiological Indicators in Patients after CABG Surgery: A Clinical Trial Study. Indian J Crit Care Med 2021; 25 (4):429-434.
Background: Sleep disorders occur in the first days after heart surgery. One of the major causes of sleep disorders after coronary artery bypass graft (CABG) is subsequent changes in physiological indicators, such as systolic blood pressure (BP), respiratory rate (RR), saturation of oxygen (O2), and heart rate (RR). This study is aimed to determine the effect of lavender aromatherapy on patients’ sleep quality and physiological indicators after CABG.
Materials and methods: This study was a randomized clinical trial. Patients after CABG surgery were randomly allocated into the lavender and distilled water groups. Patients in the intervention group inhaled lavender while those in the control group inhaled distilled water for 10 hours. Sleep quality and physiological postoperative data were collected for 3 days. Data were analyzed using repeated measurement test, sample t-test, and Chi-square test.
Results: Repeated measurement test showed no significant difference between the lavender and distilled water groups in terms of systolic BP, RR, O2 saturation, HR, and body temperature after matching the effect of time and its interactive effect with the intervention (p > 0.05). This test revealed a significant difference between the lavender and distilled water groups in terms of sleep quality (p < 0.001), such that the sleep quality was higher in the lavender group.
Conclusion: Lavender aromatherapy can increase patients’ sleep quality after CABG surgery. However, it cannot completely treat sleep disorders in such patients. Furthermore, aromatherapy with lavender does not affect the physiological parameters, such as HR, BP, RR, and O2 saturation.
Williams MA. American Association of Cardiovascular and Pulmonary Rehabilitation guideline for cardiac rehabilitation and secondary prevention programs. 4th ed. Human Kinetics; 2004.
Babaee GKM, Heidarnia A. Evaluation of quality of life in patients with coronary artery bypass surgery using controlled clinical trial. Acta Med Iran 2007;45(1):69–75.
Choudhury M, Gupta A, Hote MP, Kapoor PM, Khanna S, Kalaivani MV, et al. Does sleep quality affects the immediate clinical outcome in patients undergoing coronary artery bypass grafting: a clinico-biochemical correlation. Ann Card Anaesth 2017;20(2):193–199. DOI: 10.4103/aca.ACA_30_17.
Abbaszadeh Y, Allahbakhshian A, Seyyedrasooli A, Sarbakhsh P, Goljarian S, Safaei N. Effects of foot reflexology on anxiety and physiological parameters in patients undergoing coronary artery bypass graft surgery: a clinical trial. Complement Ther Clin Pract 2018;31:220–228. DOI: 10.1016/j.ctcp.2018.02.018.
Greve H, Pedersen PU. Improving sleep after open-heart surgery: effectiveness of nursing interventions. J Nurs Educ Pract 2016;6:15–25. DOI: 10.5430/jnep.v6n3p15.
Ghorbani A, Hajizadeh F, Sheykhi MR, Poor Asl AM. The effects of deep-breathing exercises on postoperative sleep duration and quality in patients undergoing coronary artery bypass graft (CABG): a randomized clinical trial. J Caring Sci 2018;8(4):219–224. DOI: 10.15171/jcs.2019.031.
Abad VC, Guilleminault C. Pharmacological treatment of sleep disorders and its relationship with neuroplasticity. Curr Top Behav Neurosci 2015;25:503–553. DOI: 10.1007/7854_2014_365.
Sowparnika GC, Thirumarimurugan M, Sivakumar VM, Vinoth N. Controlled infusion of intravenous cardiac drugs using global optimization. Indian J Pharmacol 2019;51(1):61–71. DOI: 10.4103/ijp.IJP_612_18.
Mistraletti G, Carloni E, Cigada M, Zambrelli E, Taverna M, Sabbatici G, et al. Sleep and delirium in the intensive care unit. Minerva Anestesiol 2008;74(6):329–333. PMID: 18500209.
Cronin AJ, Keifer JC, Davies MF, King TS, Bixler EO. Postoperative sleep disturbance: influences of opioids and pain in humans. Sleep Med Clin 2001;24(1):39–44. DOI: 10.1093/sleep/24.1.39.
Jacobi J, Fraser GL, Coursin DB, Riker RR, Fontaine D, Wittbrodt ET, et al. Clinical practice guidelines for the sustained use of sedatives and analgesics in the critically ill adult. Crit Care Med 2002;30(1):119–141. DOI: 10.1097/00003246-200201000-00020.
Perry R, Terry R, Watson LK, Ernst E. Is lavender an anxiolytic drug? A systematic review of randomised clinical trials. Phytomedicine 2012;19(8–9):825–835. DOI: 10.1016/j.phymed.2012.02.013.
Lytle J, Mwatha C, Davis KK. Effect of lavender aromatherapy on vital signs and perceived quality of sleep in the intermediate care unit: a pilot study. Am J Crit Care 2014;23(1):24–29. DOI: 10.4037/ajcc2014958.
Hasanzadeh F, Kashouk NM, Amini S, Asili J, Emami SA, Vashani HB, et al. The effect of cold application and lavender oil inhalation in cardiac surgery patients undergoing chest tube removal. EXCLI J. 2016;15:64–74. DOI: 10.17179/excli2015-748.
Hassanzadeh M, Sajadi SA, Farsi Z. Comparison effect of Sedamin capsule and inhaling Lavender essence on sleep quality of hospitalized patients in cardiac care unit. Mil Caring Sci 2018;4(3):187–197. DOI: 10.29252/mcs.4.3.187.
Salamati A, Mashouf S, Mojab F. Effect of inhalation of lavender essential oil on vital signs in open heart surgery ICU. Iran J Pharm Res 2017;16(1):404–409. PMID: 28496494. PMCID: PMC5423266.
Rajai N, Sajadi SA, Teymouri F, Zareiyan A, Siavoshi S, Malmir M. The effect of aromatherapy with lavender essential oil on anxiety and stress in patients undergoing coronary artery bypass graft surgery. Jundishapur J Chronic Dis Care 2016;5(4):e34035. DOI: 10.17795/jjcdc-34035.
Bikmoradi A, Seifi Z, Poorolajal J, Araghchian M, Safiaryan R, Oshvandi K. Effect of inhalation aromatherapy with lavender essential oil on stress and vital signs in patients undergoing coronary artery bypass surgery: a single-blinded randomized clinical trial. Complement Ther Med 2015;23(3):331–338. DOI: 10.1016/j.ctim.2014.12.001.
Moeini M, Khadibi M, Bekhradi R, Mahmoudian SA, Nazari F. Effect of aromatherapy on the quality of sleep in ischemic heart disease patients hospitalized in intensive care units of heart hospitals of the Isfahan university of medical sciences. Iran J Nurs Midwifery Res 2010;12(4):234. PMCID: PMC3203283. PMID: 22049287.
Pien GW, Sammel MD, Freeman EW, Lin H, DeBlasis TL. Predictors of sleep quality in women in the menopausal transition. Sleep 2008;31(7):991–999. PMID: 18652094. PMCID: PMC2491505.
Cheraghbeigi N, Modarresi M, Rezaei M, Khatony A. Comparing the effects of massage and aromatherapy massage with lavender oil on sleep quality of cardiac patients: A randomized controlled trial. Complement Ther Clin Pract 2019;35:253–258. DOI: 10.1016/j.ctcp.2019.03.005.
Asgari MR, Vafaei-Moghadam A, Babamohamadi H, Ghorbani R, Esmaeili R. Comparing acupressure with aromatherapy using Citrus aurantium in terms of their effectiveness in sleep quality in patients undergoing percutaneous coronary interventions: a randomized clinical trial. Complement Ther Clin Pract 2020;38:101066. DOI: 10.1016/j.ctcp.2019.101066.
Donelli D, Antonelli M, Bellinazzi C, Gensini GF, Firenzuoli F. Effects of lavender on anxiety: a systematic review and meta-analysis. Phytomedicine 2019;65:153099. DOI: 10.1016/j.phymed.2019.153099.
Abdelhakim AM, Hussein AS, Doheim MF, Sayed AK. The effect of inhalation aromatherapy in patients undergoing cardiac surgery: a systematic review and meta-analysis of randomized controlled trials. Complement Ther Med 2020;48:102256. DOI: 10.1016/j.ctim.2019.102256.
Ebrahimi Hosein Abadi S, Paryad E, Ghanbari Khanghah A, Pasdaran A, Kazem Nezhad Leyli E, Sadeghi Meibodi AM. Effects of aromatherapy using lavender oil on hemodynamic indices after coronary artery bypass graft surgery. J Holist Nurs Midwifery 2018;28(3):163–170. DOI: 10.29252/hnmj.28.3.163.