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VOLUME 25 , ISSUE 6 ( June, 2021 ) > List of Articles


Antibiotic misuse during COVID-19 Pandemic: A Recipe for Disaster

Citation Information : Antibiotic misuse during COVID-19 Pandemic: A Recipe for Disaster. Indian J Crit Care Med 2021; 25 (6):617-619.

DOI: 10.5005/jp-journals-10071-23862

License: CC BY-NC 4.0

Published Online: 01-06-2021

Copyright Statement:  Copyright © 2021; Jaypee Brothers Medical Publishers (P) Ltd.


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  1. Zhou F, Yu T, Du R, Fan G, Liu Y, Liu Z. Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study. Lancet 2020;395:1054–1062. DOI: 10.1016/S0140-6736(20)30566-3.
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  4. Hughes S, Troise O, Donaldson H, Mughal N, Moore LSP. Bacterial and fungal coinfection among hospitalized patients with COVID-19: a retrospective cohort study in a UK secondary-care setting. Clin Microbiol Infect 2020;26:1395–1399. DOI: 10.1016/j.cmi.2020.06.025.
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  6. Vaughn VM, Gandhi T, Petty LA, Patel PK, Prescott HC, Malani AN, et al. Empiric antibacterial therapy and community-onset bacterial co-infection in patients hospitalized with COVID-19: a multi-hospital cohort study. Clin Infect Dis 2020;2020:ciaa1239. DOI: 10.1093/cid/ciaa1239.
  7. Nori P, Cowman K, Chen V, Bartash R, Szymczak W, Madaline T, et al. Bacterial and fungal co-infections in COVID-19 patients hospitalized during the New York City Pandemic Surge. Infect Control Hosp Epidemiol 42(1):84-88. DOI: 10.1017/ice.2020.368.
  8. Henry BM, De Oliveira MHS, Benoit S, Plebani M, Lippi G. Hematologic, biochemical and immune biomarker abnormalities associated with severe illness and mortality in coronavirus disease 2019 (COVID-19): a meta-analysis. Clin Chem Lab Med 2020;58:1021–1028. DOI: 10.1515/cclm-2020-0369.
  9. Pulia MS, Wolf I, Schulz LT, Pop-Vicas A, Schwei RJ, Lindenauer PK. COVID-19: an emerging threat to antibiotic stewardship in the emergency department. West J Emerg Med 2020;21:1283–1286. DOI: 10.5811/westjem.2020.7.48848.
  10. Poston JT, Patel BK, Davis AM. Management of critically ill adults with COVID-19. JAMA 2020;323:1839–1841. DOI: 10.1001/jama.2020.4914.
  11. Buetti N, Mazzuchelli T, Priore EL, Balmelli C, Llamas M, Pallanza M, et al. Early administered antibiotics do not impact mortality in critically ill patients with COVID-19. J Infect 2020;81:e148–e149. DOI: 10.1016/j.jinf.2020.06.004.
  12. Guaraldi G, Meschiari M, Cozzi-Lepri A. Tocilizumab in patients with severe COVID-19: a retrospective cohort study. Lancet Rheumatol 2020;2020:E474–E484. DOI: 10.1016/S2665-9913(20)30173-9.
  13. Murray PR, Masur H. Current approaches to the diagnosis of bacterial and fungal bloodstream infections in the intensive care unit. Crit Care Med 2012;40:3277–3282. DOI: 10.1097/CCM.0b013e318270e771.
  14. Williams P, McWilliams C, Soomro K. The dynamics of procalcitonin in COVID-19 patients admitted to intensive care unit- a multi-center cohort study in the south west of England, UK. J Infect 2021;4:31. DOI: 10.1016/j.jinf.2021.03.011.
  15. Van Berkel M, Kox M, Frenzel T, Pickkers P, Schouten J. Biomarkers for antimicrobial stewardship: a reappraisal in COVID-19 times? Crit Care 2020;24:600. DOI: 10.1186/s13054-020-03291-w.
  16. Williams EJ, Mair L, de Silva TI, Green DJ, House P, Cawthron K, et al. Evaluation of procalcitonin as a contribution to antimicrobial stewardship in SARS-Cov-2 infection: a retrospective cohort study. J Hosp Infect 2021;110:103–107. DOI: 10.1016/j.jhin.2021.01.006.
  17. Dhesi Z, Enne VI, Brealey D. Organisms causing secondary pneumonia in COVID-19 patients in 5 UK ICUs as detected with the film Array test. Available at:
  18. Kayarat B, Khanna P, Sarkar S. Superadded Coinfections and Antibiotic Resistance in the Context of COVID-19: Where do We stand? Indian J Crit Care Med 2021;25(6):698–702.
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