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VOLUME 25 , ISSUE 9 ( September, 2021 ) > List of Articles


Intensive Care Unit-acquired Weakness: A Frequent but Under-recognized Threat

Citation Information : Intensive Care Unit-acquired Weakness: A Frequent but Under-recognized Threat. Indian J Crit Care Med 2021; 25 (9):969-971.

DOI: 10.5005/jp-journals-10071-23990

License: CC BY-NC 4.0

Published Online: 08-09-2021

Copyright Statement:  Copyright © 2021; The Author(s).


  1. Baby S, George C, Osahan NM. Intensive Care Unit-acquired Neuromuscular Weakness: A Prospective Study on Incidences, Clinical Course, and Outcomes. Indian J Crit Care Med 2021;25(9):1006–1012.
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  4. Baum P, Bercker S, Villmann T, Classen J, Hermann W. Critical-illness-Myopathie und -Neuropathie (CRIMYN). Elektroneurographische Klassifikation [Critical illness myopathy and neuropathy (CRIMYN). Electroneurographic classification]. Nervenarzt 2011;82(4):468–474. DOI: 10.1007/s00115-010-3094-5.
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  7. Qian Z, Yang M, Li L, Chen Y. Ultrasound assessment of diaphragmatic dysfunction as a predictor of weaning outcome from mechanical ventilation: a systematic review and meta-analysis. BMJ Open 2018;8(9):e021189. DOI: 10.1136/bmjopen-2017-021189.
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  9. Yang T, Li Z, Jiang L, Wang Y, Xi X. Risk factors for intensive care unit-acquired weakness: a systematic review and meta-analysis. Acta Neurol Scand 2018;138(2):104–114. DOI: 10.1111/ane.12964.
  10. Yang T, Li Z, Jiang L, Xi X. Corticosteroid use and intensive care unit-acquired weakness: a systematic review and meta-analysis. Crit Care 2018;22(1):187. DOI: 10.1186/s13054-018-2111-0.
  11. Hermans G, Wilmer A, Meersseman W, Milants I, Wouters PJ, Bobbaers H, et al. Impact of intensive insulin therapy on neuromuscular complications and ventilator dependency in the medical intensive care unit. Am J Respir Crit Care Med 2007;175(5):480–489. DOI: 10.1164/rccm.200605-665OC.
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  13. Hermans G, Van Mechelen H, Clerckx B, Vanhullebusch T, Mesotten D, Wilmer A, et al. Acute outcomes and 1-year mortality of intensive care unit-acquired weakness. A cohort study and propensity-matched analysis. Am J Respir Crit Care Med 2014;190(4):410–420. DOI: 10.1164/rccm.201312-2257OC.
  14. Hermans G, De Jonghe B, Bruyninckx F, Van den Berghe G. Interventions for preventing critical illness polyneuropathy and critical illness myopathy. Cochrane Database Syst Rev 2009;(1):CD006832. DOI: 10.1002/14651858.CD006832.pub2.
  15. Kho ME, Truong AD, Zanni JM, Ciesla ND, Brower RG, Palmer JB, et al. Neuromuscular electrical stimulation in mechanically ventilated patients: a randomized, sham-controlled pilot trial with blinded outcome assessment. J Crit Care 2015;30(1):32–39. DOI: 10.1016/j.jcrc.2014.09.014.
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