Indian Journal of Critical Care Medicine

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VOLUME 25 , ISSUE 9 ( September, 2021 ) > List of Articles

LETTER TO THE EDITOR

Differing Sensitivity of COVID-19 PCR Tests and Consequences of the False-negative Report: A Small Observation

Sunil K Garg

Keywords : COVID-19 infection, COVID-19 patient, Diagnosis test, SARS-CoV-2 RT-PCR

Citation Information : Garg SK. Differing Sensitivity of COVID-19 PCR Tests and Consequences of the False-negative Report: A Small Observation. Indian J Crit Care Med 2021; 25 (9):1077-1078.

DOI: 10.5005/jp-journals-10071-23937

License: CC BY-NC 4.0

Published Online: 08-09-2021

Copyright Statement:  Copyright © 2021; Jaypee Brothers Medical Publishers (P) Ltd.


Abstract

The world at large cannot afford to miss even a single case of COVID-19 because of its far-reaching consequences; therefore, the diagnostic development to achieve test with much higher sensitivity should be made available at a mass level as early as possible.


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  1. FDA permits marketing of first SARS-CoV-2 diagnostic test using traditional premarket review process FDA. 2021 (accessed 2 May 2021).
  2. Arevalo-Rodriguez I, Buitrago-Garcia D, Simancas-Racines D, Zambrano-Achig P, del Campo R, Ciapponi A, et al. False-negative results of initial RT-PCR assays for COVID-19: a systematic review. medRxiv. 2020. DOI: 10.1101/2020.04.16.20066787.
  3. Kinloch NN, Ritchie G, Brumme CJ, Dong W, Dong W, Lawson T, et al. Suboptimal biological sampling as a probable cause of false-negative COVID-19 diagnostic test results. J Infect Dis 2020;222(6):899–902. DOI: 10.1093/infdis/jiaa370.
  4. Kucirka LM, Lauer SA, Laeyendecker O, Boon D, Lessler J. Variation in false-negative rate of reverse transcriptase polymerase chain reaction-based SARS-CoV-2 tests by time since exposure. Ann Intern Med 2020;173(4):262–267. DOI: 10.7326/M20-1495.
  5. Prinzi A. False negatives and reinfections: the challenges of SARS-CoV-2 RT-PCR testing. https://asm.org/Articles/2020/April/False-Negatives-and-Reinfections-the-Challenges-of (accessed 5 July 2020).
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