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VOLUME 26 , ISSUE 2 ( February, 2022 ) > List of Articles


Colistin-induced Bartter-like Syndrome: Ponder before Treatment!

Anju Kumari, Poonam Gupta, Himanshu Verma, Ajay Kumar, Preeti Thakur, Kavish Sharma

Keywords : Bartter-like syndrome, Colistin, Critically ill patients

Citation Information : Kumari A, Gupta P, Verma H, Kumar A, Thakur P, Sharma K. Colistin-induced Bartter-like Syndrome: Ponder before Treatment!. Indian J Crit Care Med 2022; 26 (2):239-243.

DOI: 10.5005/jp-journals-10071-24117

License: CC BY-NC 4.0

Published Online: 09-02-2022

Copyright Statement:  Copyright © 2022; The Author(s).


Bartter-like syndrome (BLS) is a constellation of biochemical abnormalities which include metabolic alkalosis, hypokalemia, hypocalcemia, hypomagnesemia with normal kidney function. BLS is a very rare syndrome and can be induced by certain diseases, antibiotics, diuretics, and antineoplastic drugs. Colistin is a polymicrobial bactericidal drug and currently re-emerged as the only salvation therapy against multidrug resistant bacilli especially in critically ill patients at intensive care units. Only an anecdotal case report of colistin-induced Bartter-like syndrome has been reported. We here report a case series of four critically ill patients who were on treatment with colistin and presented with serious metabolic disturbances.

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