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VOLUME 26 , ISSUE 4 ( April, 2022 ) > List of Articles


A Fatal Case of Acute Disseminated Encephalomyelitis: A Diagnosis to Ponder in Pandemic

Vinod K Singh, Brijendra K Rao

Keywords : Acute disseminated encephalomyelitis, COVID-19, Vaccine

Citation Information : Singh VK, Rao BK. A Fatal Case of Acute Disseminated Encephalomyelitis: A Diagnosis to Ponder in Pandemic. Indian J Crit Care Med 2022; 26 (4):520-522.

DOI: 10.5005/jp-journals-10071-24185

License: CC BY-NC 4.0

Published Online: 13-05-2022

Copyright Statement:  Copyright © 2022; The Author(s).


A 40-year-old woman known hypertensive presented with progressive ascending paralysis. MRI T2W and FLAIR screening of the brain demonstrated swelling with altered signal in the visual cervical cord, medulla, and another juxtacortical lesion in the right temporal lobe with possibility of a demyelinating etiology. CSF testing did not identify a direct cerebral infection. High-dose steroids followed by a course of IVIG was administered but with no significant response. In these pandemic times, the patients who present with altered mentation and polyfocal neurological deficits and background history of recent COVID-19 infection or recipient of SARS-CoV-2 vaccine the diagnosis of acute disseminated encephalomyelitis (ADEM) should be considered likely.

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