Indian Journal of Critical Care Medicine

Register      Login

SEARCH WITHIN CONTENT

FIND ARTICLE

Volume / Issue

Online First

Archive
Related articles

VOLUME 27 , ISSUE 12 ( December, 2023 ) > List of Articles

PEDIATRIC CRITICAL CARE MEDICINE

Clinical Profile of Children with Burns in a Tertiary Care Hospital

K Yashaswini, AV Lalitha, GS Naresh Kanna, Abha Rani Kujur, John A Michael Raj

Keywords : Fluids, Mortality, Total burns surface area

Citation Information : Yashaswini K, Lalitha A, Kanna GN, Kujur AR, Michael Raj JA. Clinical Profile of Children with Burns in a Tertiary Care Hospital. Indian J Crit Care Med 2023; 27 (12):934-938.

DOI: 10.5005/jp-journals-10071-24592

License: CC BY-NC 4.0

Published Online: 30-11-2023

Copyright Statement:  Copyright © 2023; The Author(s).


Abstract

Background: Optimal resuscitation measures and outcome predictors in cases of burns are not studied in pediatric population, though it accounts for one of the leading causes of non-fatal injuries in the pediatric age group. Objective: We describe the clinical profile and outcome predictors in children admitted with burns. Materials and methods: This retrospective cohort study included all children between 1 month and 18 years admitted to pediatric intensive care unit (PICU) with burns from January 2015 to December 2020. The total burns surface area (TBSA) was assessed and treated as per unit protocol. Illness severity score (PRISM III) and pediatric logistic organ dysfunction (PELOD-II) on day 1 and subsequently was noted. Resuscitation requirements including inotropes and colloids were evaluated. Outcome parameters like need for mechanical ventilation, renal replacement therapy, duration of hospital stay, PICU stay, and mortality were assessed. Results: Of 286 children admitted with burns, 99 had PICU admissions, and of these 59% were males with median (IQR) age 36 (13,72) months. Multivariate logistic regression analysis showed TBSA >40% [adjusted odds ratio (AOR) 4.62 [1.11–19.32] p-value < 0.036]. Cox regression for 28 day mortality was significant only for PELOD day 1 (heart rate (HR) 1.22 [1.05–1.41]). Conclusion: Higher resuscitation requirements with higher organ dysfunction scores may predict mortality in pediatric burns warranting further study for standardization of care.


HTML PDF Share
  1. The problem of burns in India. Davies JWL. Burns 1990;17 (Suppl. 1): S1–24. PMID: 2282149.
  2. Chelidze KI, Lim CC, Peck RN, Giiti G, Leahy N, Rabbitts A, et al. Predictors of mortality among Pediatric burn patients in East Africa. J Burn Care Res 2016;37(2):e154–160. DOI: 10.1097/BCR.0000000000000286.
  3. Wolf SE, Rose JK, Desai MH, Mileski JP, Barrow RE, Herndon DN. Mortality determinants in massive pediatric burns. An analysis of 103 children with > or = 80% TBSA burns (> or = 70% full-thickness). Ann Surg 1997; 225(5): 554–565. DOI: 10.1097/00000658-199705000-00012.
  4. Tan Chor Lip H, Tan JH, Thomas M, Imran FH, Azmah Tuan Mat TN. Survival analysis and mortality predictors of hospitalized severe burn victims in a Malaysian burns intensive care unit. Burns and trauma 2019;7:3. DOI: 10.1186/s41038-018-0140-1.
  5. Ganesamoni S, Kate V, Sadasivan J. Epidemiology of hospitalized burn patients in a tertiary care hospital in South India. Burns 2010;36(3):422–429. DOI: 10.1016/j.burns.2009.06.212.
  6. Pollack MM, Patel KM, Ruttimann UE. PRISM III: An updated pediatric risk of mortality score. Crit Care Med 1996;24(5):743–752. DOI: 10.1097/00003246-199605000-00004.
  7. Gaies MG, Gurney JG, Yen AH, Napoli ML, Gajarski RJ, Ohye RG, et al. Vasoactive-inotropic score as a predictor of morbidity and mortality in infants after cardiopulmonary bypass. Pediatr Crit Care Med 2010;11(2):234–238. DOI: 10.1097/PCC.0b013e3181b806fc.
  8. Murari A, Singh KN. Lund and Browder chart—modified versus original: A comparative study. Acute Crit Care 2019;34(4):276–281. DOI: 10.4266/acc.2019.00647.
  9. Haberal M, Sakallioglu Abali AE, Karakayali H. Fluid management in major burn injuries. Indian J Plast Surg 2010;43:S29–36. DOI: 10.4103/0970-0358.70715.
  10. Cancio LC, Lundy JB, Sheridan RL. Evolving changes in the management of burns and environmental injuries. Surg Clin North Am 2012;92(4):959–986. DOI: 10.1016/j.suc.2012.06.002.
  11. Comish P, Walsh M, Castillo-Angeles M, Kuhlenschmidt K, Carlson D, Arnoldo B, et al. Adoption of rescue colloid during burn resuscitation decreases fluid administered and restores end organ perfusion. Burns 2021;47(8):1844–1850. DOI: 10.1016/j.burns.2021.02.005.
  12. Messmer AS, Zingg C, Müller M, Gerber JL, Schefold JC, Pfortmueller CA. Fluid overload and mortality in adult critical care patients—a systematic review and meta-analysis of observational studies. Crit Care Med 2020;48(12):1862–1870. DOI: 10.1097/CCM. 0000000000004617.
  13. Leteurtre S, Duhamel A, Salleron J, Grandbastien B, Lacroix J, Leclerc F, et al. PELOD-2: An update of the pediatric logistic organ dysfunction score. Crit Care Med 2013;41(7):1761–1773. DOI: 10.1097/CCM.0b013e31828a2bbd.
  14. Chacko J, Jahan N, Brar G, Moorthy R. Isolated inhalational injury: Clinical course and outcomes in a multidisciplinary intensive care unit. Indian J Crit Care Med 2012;16(2):93–99. DOI: 10.4103/0972-5229.99120.
  15. Romanowski KS, Palmeiri TL. Pediatric burns resuscitation: past, present and future. Burns and Trauma 2017;5:26. DOI: 10.1186/s41038-017-0091-y.
  16. Cochrane Injuries Group Albumin Reviewers. Human albumin administration in critically ill patients; systematic review of randomized control trials. BMJ 1998;317(7153):235–240. DOI: 10.1136/bmj.317.7153.235.
  17. Cochran A, Morris SE, Edelman LS, Saffle JR. Burn patient characteristics and outcomes following resuscitation with albumin. Burns 2007; 33(1): 25–30. DOI: 10.1016/j.burns.2006.10.005.
  18. Lawrence A, Faraklas I, Watkins H, Allen A, Cochran A, Morris S, et al. Colloid administration normalizes resuscitation ratio and ameliorates ‘fluid creep’. J Burn Care Res 2010;31(1):40–47. DOI: 10.1097/BCR.0b013e3181cb8c72.
  19. Navickis RJ, Greenhalgh DG, Wilkes MM. Albumin in burn shock resuscitation: a meta-analysis of controlled clinical trials. J Burn Res 2016;37(3):e268–e278. DOI: 10.1097/BCR.0000000000000201.
  20. Kamolz LP, Andel H, Schramm W, Meissl G, Herndon DN, Frey M. Lactate: Early predictor of morbidity and mortality in patients with severe burns. Burns 2005;31(8):986–990. DOI: 10.1016/j.burns.2005.06.019.
  21. Andel D, Andel H, Roka J, Schramm W, Zimpfer M, Frey M, et al. Base deficit and lactate: early predictors of morbidity and mortality in-patients with burns. Burns 2007;33(8):973–978. DOI: 10.1016/j.burns.2007.06.016.
  22. Patel BM, Paratz JD, Mallet A, Lipman J, Rudd M, Muller MJ, et al. Characteristics of bloodstream infections in burn patients: an 11-year retrospective study. Burns 2012; 38(5): 685–690. DOI: 10.1016/j.burns.2011.12.018.
  23. Ebenezer R, Princess I, Vadala R, Kumar S, Ramakrishnan N, Krishnan G. Microbiological profile of infections in a tertiary care burns unit. Indian J Crit Care Med 2019;23(9):405–410. DOI: 10.5005/jp-journals-10071-23234.
  24. Taylor SL, Lawless M, Curri T, Sen S, Greenhalgh DG, Palmieri TL. Predicting mortality from burns: the need for age-group specific models. Burns 2014;40(6):1106–1115. DOI: 10.1016/j.burns.2014. 03.010.
PDF Share
PDF Share

© Jaypee Brothers Medical Publishers (P) LTD.